Résumé
An 82 year old man developed antibodies against coagulation factor VIII:C without any apparent cause. Bleeding from the soft tissue cavity could not be controlled by factor VIII:C concentrates, immunosuppression with steroids and intravenous immunoglobulin therapy in the standard dosages. However, a single injection of Epsilon Aminocaproic Acid (EACA) instilled into the cavity under aseptic precautions achieved lasting hemostasis with resultant wound healing.
Sujets)
Acide 6-amino-caproïque/usage thérapeutique , Sujet âgé , Sujet âgé de 80 ans ou plus , Antifibrinolytiques/usage thérapeutique , Autoanticorps/immunologie , Facteur VIII/immunologie , Hémophilie A/complications , Hémorragie/traitement médicamenteux , Humains , Instillation de médicaments , MâleRésumé
Ischemic events have been reported to follow a circadian rhythm. The frequency of myocardial infarction is found to be increased between 6:01 a.m. and 2:00 p.m. Blood pressure also demonstrates a similar circadian variation. Circadian variation of stroke onset has also been reported, but with contradictory findings. To determine this in the Indian population, we studied 182 consecutive patients of acute stroke admitted to our words within twelve hours of onset. The frequency of onset of stroke was found to be highest between 6:01 am and 2:00 pm, in patients of infarct as well as haemorrhage. Patients of hypertension also showed a similar variation. Thus, the identification of periods of high risk, may help by matching drug doses with periods of vulnerability.
Sujets)
Maladie aigüe , Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Angiopathies intracrâniennes , Rythme circadien , Femelle , Humains , Mâle , Adulte d'âge moyen , Facteurs tempsRésumé
Porencephalic cyst with seizure is rare. It represents a part of diffuse cerebral maldevelopment. Porencephaly occurs as a result of imbalance between brain growth and its vascular supply and is picked up by CT scan.