Résumé
A case of osteoclastoma like giant cell tumour of thyroid is reported in a patient who presented with dysphagia and swelling in the neck. The light microscopy showed numerous osteoclast-like giant cells embedded in mononuclear stromal cells, the overall appearance resembling that of giant cell tumour of bone.
Sujets)
Sujet âgé , Carcinomes/diagnostic , Femelle , Tumeur osseuse à cellules géantes/diagnostic , Humains , Tumeurs de la thyroïde/diagnosticSujets)
Animaux , Columbidae , Femelle , Glucose/métabolisme , Absorption intestinale/effets des médicaments et des substances chimiques , Intestins/effets des médicaments et des substances chimiques , Mâle , Transporteurs de monosaccharides/métabolisme , Phlorétine/pharmacologie , Phloridzine/pharmacologieRésumé
Development of malignancy in the trophic ulcer in leprosy is not previously believed rare. In India, less than a dozen cases are reported uptil now. We present a case of squamous cell carcinoma in trophic ulcer in leprosy patient because of its paucity in literature. Aetiopathogenesis of malignancy is discussed briefly.
Sujets)
Carcinome épidermoïde/étiologie , Pied , Maladies du pied/complications , Humains , Lèpre/complications , Mâle , Adulte d'âge moyen , Tumeurs cutanées/étiologie , Ulcère cutané/complicationsSujets)
Alanine/métabolisme , Animaux , Transport biologique/effets des médicaments et des substances chimiques , Columbidae , Glucose/métabolisme , Glycine/métabolisme , Indoles/pharmacologie , Intestins/effets des médicaments et des substances chimiques , Isatine/pharmacologie , Sodium/pharmacologieRésumé
A bilaterally synchronous 3/sec spike and wave pattern in the EEG can be obtained during stimulation of the nucleus medialis dorsalis (nMD) and nucleus paracentralis (nPC) of the thalamus, in lightly anaesthetized juvenile monkeys. The spike and wave EEG patterns have a frequency of 2 1/2 to 3Hz and occur during low frequency stimulation, without continuing into the post-stimulatory phase. Stimulation of the mesencephalic reticular formation (MRF) at higher voltages inhibits the thalamic-induced spike and wave response. This finding has heuristic significance, as activating stimuli arrest the wave and spike EEG pattern of human absence (petit mal epilepsy) seizures. The study also demonstrates the morphological similarity of the 3/sec spike and wave thalamic induced response in experimental and clinical absence states as well as similarities in their alterations with different levels of activation.
Sujets)
Anesthésie , Animaux , Stimulation électrique , Électroencéphalographie , Macaca mulatta , Formation réticulaire/physiologie , Noyaux du thalamus/physiologie , Thalamus/physiologieRésumé
The behavioural and electroencephalographic responses resulting from stimulation of a specific area in the nucleus medialis dorsalis (nMD) of unanaesthetized juvenile Rhesus monkeys is described. A behavioural arrest reaction, lack of awareness and motor inhibition with concomitant 2 1/2 to 3Hz spike and wave EEG afterdischarge patterns were obtained by stimulation of the nMD in monkeys with bilaterally symmetrical aluminium hydroxide Al (OH)3 lesions in anterior premotor cortical areas.