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Rev. Soc. Bras. Med. Trop ; 51(3): 352-356, Apr.-June 2018. tab
Article Dans Anglais | LILACS | ID: biblio-1041467

Résumé

Abstract INTRODUCTION We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients. METHODS: Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil. RESULTS: Oral lesions, mainly pseudomembranous, were significantly related to higher levels of immunosuppression. Of 45 Candida isolates, 66.7% were C. albicans. Most of the isolates were susceptible to the antifungal drugs tested. CONCLUSIONS: Oral lesions were associated with higher immunosuppression levels. Lower susceptibility to antifungals by non-albicans isolates supports the importance of surveillance studies using susceptibility tests to aid in the treatment.


Sujets)
Humains , Mâle , Femelle , Adulte , Jeune adulte , Candida/effets des médicaments et des substances chimiques , Candidose buccale/diagnostic , Infections opportunistes liées au SIDA/diagnostic , Antifongiques/pharmacologie , Brésil , Candida/isolement et purification , Candida/classification , Candidose buccale/microbiologie , Résistance microbienne aux médicaments , Tests de sensibilité microbienne , Fluconazole/pharmacologie , Amphotéricine B/pharmacologie , Techniques de typage mycologique , Infections opportunistes liées au SIDA/microbiologie , Itraconazole/pharmacologie , Adulte d'âge moyen
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