1.
Indian J Biochem Biophys
;
1990 Aug; 27(4): 240-4
Article
Dans Anglais
| IMSEAR
| ID: sea-26377
Résumé
Binding of chlorpromazine (CPZ), a widely used antidepressant tranquilizer, with hemoglobin has been studied by equilibrium dialysis method. r/Cf versus r plot was typically concave downwards revealing the positive cooperative nature of binding. Binding parameters, namely the affinity constant (K) and the degree of cooperativity (nH) were determined from the Hill plot. Oxygen was found to be released gradually from hemoglobin with gradual addition of CPZ, the extent of oxygen release depending on the stoichiometric ratio of CPZ: hemoglobin (D/P).
Sujets)
Sites de fixation , Chlorpromazine/métabolisme , Hémoglobines/effets des médicaments et des substances chimiques , Humains , Cinétique , Oxygène/métabolisme
2.
Indian Heart J
;
1986 Mar-Apr; 38(2): 155-7
Article
Dans Anglais
| IMSEAR
| ID: sea-4728
Sujets)
Adulte , Cardiomégalie/diagnostic , Diagnostic différentiel , Femelle , Atrium du coeur , Humains
3.
Indian Heart J
;
1983 Nov-Dec; 35(6): 366-8
Article
Dans Anglais
| IMSEAR
| ID: sea-3730