Résumé
Choroidal osteoma is an unusual form of intraocular calcification seen in otherwise healthy eyes. It is a benign idiopathic osseous tumor of the choroid, typically seen in young females. Choroidal neovascular membrane (CNVM) is a complication seen in one-third of these patients and carries a poor visual outcome. We report a case of a 25-year-old hyperthyroid female with choroidal osteoma and subfoveal CNVM in her left eye which was successfully treated using low-fluence photodynamic therapy (PDT) with verteporfin followed by a single injection of intravitreal ranibizumab.
Sujets)
Adulte , ANTIBODIES, MONOCLONAL, HUMANIZED ADMINISTRATION & , Tumeurs osseuses/complications , Tumeurs osseuses/diagnostic , Tumeurs osseuses/traitement médicamenteux , Tumeurs de la choroïde/complications , Tumeurs de la choroïde/diagnostic , Tumeurs de la choroïde/traitement médicamenteux , Néovascularisation choroïdienne/diagnostic , Néovascularisation choroïdienne/traitement médicamenteux , Néovascularisation choroïdienne/étiologie , Diagnostic différentiel , Femelle , Études de suivi , Humains , Injections intravitréennes , Microscopie acoustique , Ostéome/complications , Ostéome/diagnostic , Ostéome/traitement médicamenteux , Photothérapie dynamique/méthodes , Tomographie par cohérence optique , Acuité visuelleRésumé
Angioid streaks also called Knapp striae are small breaks in the Bruch's membrane and have been reported with a host of systemic diseases. Rupture of streaks or development of secondary choroidal neovascular membrane (CNVM) carries a dismal visual prognosis. We report the successful treatment of CNVM secondary to Paget's disease using low fluence photodynamic therapy (PDT) and intravitreal ranibizumab.