Résumé
Objective To investigate the effect of Zhibaidihuangwan combined with clindamycin hydrochloride on serum IL-8, TNF-α, IL-10 levels in periodontitis and its clinical efficacy.Methods A total of 98 patients with periodontitis from our hospital were collected and randomly divided into the control group and the experimental group, 49 cases each group.Patients in the control group were treated on the basis of the foundation therapy with clindamycin hydrochloride, patients in the experimental group were treated with Zhibaidihuangwan on the basis of control group .The periodontal pocket depth, plaque index, gingival index and positive rate of probe bleeding, serum IL-8, TNF-a, IL-10 levels were measured, and the clinical efficacy were compared.Results The effective rate of the experimental group(93.88%) was higher than the control group(79.59%), with statistical significance (P<0.05).The positive rate of probe bleeding in experimental group (38.78%) was lower than control group of two groups(59.18%), with statistical significance (P<0.05).The periodontal pocket depth, plaque index, gingival index in experimental group were lower than the control group after treatment, the TNF-αand IL-8 levels in experimental group were lower than the control group, IL-10 was higher than the control group after treatment, with statistical significance (P<0.05).Conclusion Zhibaidihuangwan combined with clindamycin hydrochloride could reduce periodontitis serum IL-8 and TNF-αlevels, improve the level of IL-10.
Résumé
OBJECTIVE To investigate risk factors and nursing protective measures controlling hospital infection in patients after neck dissection. METHODS The data of 116 patients after neck dissection from Aug 2000 to Aug 2005 were collected, and the hospital infection condition was analyzed in comparison with non-infection group. RESULTS Hospital infection rate was 18.97% (22/116) and case-time rate was 21.55%(25/116). Of 25 occasions in hospital infections, 48% were infection of operative incision and 24% were infection of respiratory tract. The risk factors for hospital infection in patients with neck dissection might be associated with patient's duration of hospitalization, history of chronic disease , age and invasive operation. CONCLUSIONS There is a high hospital infection incidence rate in patients after neck dissection , it is necessary to monitor high risk patients.