Résumé
Objective To analyze the selection rules and characteristics of acupuncture and moxibustion in the treatment of temporomandibular disorder(TMD)based on data mining techniques.Methods Computerized search of major databases such as CNKI,Wanfang,VIP,and CBM from January 2002 to June 2022.After screening and standardized treatment of acupuncture prescriptions,data analysis was performed to explore the selection and characteristics of core acupoints.Results A total of 92 papers were included,and 108 valid prescriptions and 36 acupuncture points were extracted with a total frequency of 555 times.Among them,11 high-frequency acupoints in the top 10 of the total frequency were used,including Xiaguan(ST7),Hegu(LI4),Jiache(ST6),Tinggong(SI19),Yifeng(SJ17),Ashi,Zusanli(ST36),Quanliao(SI18),Shangguan(GB3),Fengchi(GB20),Tinghui(GB2),with a total of 481 times,accounting for 85.79%of the total frequency.The association rules showed a very strong correlation and co-occurrence between Xiaguan(ST7),Hegu(LI4),Jiache(ST6),Tinggong(SI19),and the cluster analysis yielded 4 core clusters.Conclusion Acupuncture and moxibustion for treatment of this disease mainly follows the principle of"the main treatment should reach where the meridians pass",and the core combination of selected points is:Xiaguan(ST7)-Hegu(LI4)-Jiache(ST6)-Tinggong(SI19).
Résumé
OBJECTIVE: To investigate the clinical characteristics,treatment strategies,and prognosis of aggressive fibromatosis in children. METHODS: A retrospective analysis was performed in 27 cases of aggressive fibromatosis from January 2007 to January 2018 in Beijing Children's Hospital,Capital Medical University. RESULTS: There were 16 males and 11 females in 27 cases of aggressive fibromatosis,with a median age of 65(35,96)months at diagnosis. Tumor locations were as follows: abdominal wall(n=3),abdominal cavity(n=5),and extra-abdominal(n=19). Preoperative imaging examination showed that the median maximum diameter of primary tumors was 9.8(5.3,12.1)cm. Upfront surgery was performed in all of the cases,and 10 cases received adjuvant chemotherapy combined with methotrexate and vinorelbine. Among the 27 cases,9 cases survived without disease,15 cases survived with disease,and 3 cases died of tumor recurrence or progression. The 5-year overall survival and event-free survival rates were 85.8% and 32.6%,respectively.Further analysis of survival showed that positive surgical margin was associated with tumor recurrence. CONCLUSION: Aggressive fibromatosis is a rare,intermediate tumor in children. It is easy to relapse after incomplete surgical resection.Chemotherapy plays a role in controlling the growth of tumors. Most of the children have good prognosis,but some of them may be disabled or even die because of persistent,fast-growing tumors.