Nasopharyngeal teratomas (a case report and review of the literature) / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To investigate the clinical characteristics of nasopharyngeal teratomas (NPT), improve the diagnosis and treatment of the disease.@*METHOD@#We reported a 14 years old girl with NPT, and reviewed the literatures.@*RESULT@#NPT was transorally expected under nasal endoscope, no recurrence was found over a 5 year follow-up.@*CONCLUSION@#NPT is rare,the diagnosis of the disease relies on clinical manifestations, imaging and pathological examination. Transoral endoscopic surgery is an effective method of treatment.

In vitro comparison of transdermal characteristics of xiaoyu ointment and xiaoyu plaster / 中国中药杂志

<p><b>OBJECTIVE</b>Through the comparison of Xiaoyu ointment and xiaoyu plaster by in vitro transdermal demonstrate, to demonstrate the scientificity and feasibility of reformed formulation.</p><p><b>METHOD</b>The improved Franz diffusion cells and in vitro rabbit skin were used in vitro penetration experiment with emodin as an indicator of penetration rate quantitated by HPLC.</p><p><b>RESULT</b>The cumulative penetration rate of emodin in Xiaoyu ointment fit the model of Weibull distribution, while the cumulative penetration rate of emodin in Xiaoyu plaster fit the model of Density equation. Take emodin as an index,the transdermal rate in Xiaoyu plaster was 1.93 times as Xiaoyu ointment, and the total penetrated amount was 2.84 times as Xiaoyu ointment. The results showed that the emodin of xiaoyu plaster reserved in the skin were 3.95 times more than the ointment.</p><p><b>CONCLUSION</b>The penetration rate, total penetrated amount and the reserves in the skin of Xiaoyu plaster were better than the ointment, and the transdermal dosage form was better than the original form.</p>