Clinical characteristics of non-steroidal anti-inflammatory drugs induced peptic ulcer bleeding / 实用医学杂志

Objective To study the clinical characteristics of non-steroidal anti-inflammatory drugs (NSAIDs)induced peptic ulcer bleeding(PUB). Methods The case-control study was used to analyze the clinical data of 142 patients with NSAIDs-induced PUB and 210 patients with non-NSAIDs-induced PUB. Results There were significant differences between the two groups regarding sex and age of patient,history of rheumatic diseases or cardio-cerebral-vascular disease,types and numbers of ulcer,abdominal pain,hemoglobin concentration,and hospital stay(P<0.05),but there was no obvious difference in terms of the size of ulcer,BUN and HP infection rate. Conclusion Proper measures should be employed to decrease the complications of NSAIDs-induced PUB.