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1.
Indian J Med Sci ; 2007 Aug; 61(8): 471-3
Article de Anglais | IMSEAR | ID: sea-69434

RÉSUMÉ

Purpura fulminans is a rapidly progressive thrombotic disease that has been described during both severe bacterial and viral infections. Disseminated intravascular coagulation (DIC), antiphospholipid antibodies and acquired or congenital C and S protein deficiency are thought to play a role in its pathogenesis. Here we report the case of a 4-year-old girl who developed gangrene of all her fingers and toes following dengue shock syndrome complicated by DIC and also discuss its management.


Sujet(s)
Enfant d'âge préscolaire , Dengue sévère/complications , Coagulation intravasculaire disséminée/étiologie , Femelle , Gangrène/diagnostic , Humains , 12131/diagnostic
2.
Indian J Med Microbiol ; 2007 Apr; 25(2): 143-5
Article de Anglais | IMSEAR | ID: sea-53531

RÉSUMÉ

The aim of this study was to determine the clinical characteristics and poor prognostic factors associated with high mortality in dengue encephalopathy. Fifteen patients with confirmed dengue infections, who developed encephalopathy, were recruited from two tertiary care hospitals in Colombo, Sri Lanka. Among the factors that contributed to encephalopathy were: Acute liver failure (73%), electrolyte imbalances (80%) and shock (40%). Five (33.3%) patients developed seizures. Disseminated intravascular coagulation was seen in five (33.3%). Secondary bacterial infections were observed in 8 (53.3%) of our patients. The overall mortality rate was 47%.


Sujet(s)
Adulte , Infections bactériennes/complications , Encéphalopathies/diagnostic , Enfant , Enfant d'âge préscolaire , Études de cohortes , Dengue/complications , Dengue sévère/complications , Coagulation intravasculaire disséminée/complications , Femelle , Humains , Nourrisson , Défaillance hépatique aigüe/complications , Mâle , Adulte d'âge moyen , Pronostic , Crises épileptiques/complications , Choc/complications , Sri Lanka , Troubles de l'équilibre hydroélectrolytique/complications
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