Refractory iron-deficiency anemia in a young patient a rare presentation of celiac disease

Refractory iron deficiency anemia can be an atypical presentation of celiac disease. A 24-year-old male was presented with a six year history of iron deficiency anemia, did not respond to oral iron therapy and received 21 pints of blood; upper endoscopy, duodenal biopsy and serology proved the diagnosis of celiac disease. After gluten-free diet the condition improved within two weeks and regained his normal life after 6 months with the normalization of hematological parameter and serum antibodies. The celiac disease should be considered in patient with refractory iron deficiency anemia.