Role of breast magnetic resonance imaging in early stage breast cancer

Background: globally, breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women. The surgical management of patients with early stage operable breast cancer is the main step of treatment and addresses both the primary tumor and regional lymphatics. Objectives: this study aims at highlighting the role of preoperative dynamic contrast enhanced breast MRI in early stage breast cancer and its impact on surgical management. Patients and Methods: this study was carried out over the period from March 2015 to October 2017 in Radiodiagnosis Department of Mansoura University Hospitals and Nasser Institute. The study was conducted on 29 female their ages ranging from 30 to 59 years old the study was approved by our Institution's Ethics Committee, and all patients gave their informed consent before inclusion in the study. Results: in our study, MRI was requested for different causes varying between dense breast which may obscure lesions (51.7%), multifocal lobular carcinoma (13.7%), exclude multicentric lesion (10. 3%) and in (24%) of patients MRI was requested as preoperative routine check. In our study, we found that in 10 patients (34.5%), MRI revealed additional lesions that were not seen on conventional imaging by mammography and ultrasound.Six lesions (20.7%) of those additional occult lesions were identified as malignant and all were ipsilateral. Our study reported that six patients (20. 7%) who had unsuspected abnormalities identified on MRI had changes in treatment based on MRI findings. Conclusion: the results of this study confirm previous reports that preoperative MRI of the breast alters clinical management and detects otherwise occult carcinoma in a substantial number of patients with early breast cancer

Evaluation of the haemodynamic changes in the portal and splenic veins by color doppler sonography in patients with chronic liver diseases

This study was designed to evaluate the role of color Doppler sonography in the assessment of portal hypertension in patients with chronic liver diseases by estimating the various hemodynamic parameters in portal and splenic veins including portal vein [PV] and splenic vein [SV] diameter, cross sectional area, flow velocity, congestion index [CI], volume flow and flow direction. These parameters were performed on 20 patients with chronic liver diseases [group I], 10 of them with esophageal varices [group IA] and 10 cases without esophageal varices [group IB]; also, 10 normal age and sex matched persons were included as a control group [group II]. The study concluded that color Doppler sonography is a good tool in evaluating the hemodynamic changes in patients with chronic liver disease as dilated portal vein and splenic vein diameter, reduced PV velocity and increased PV [CI] can be used for the detection and assessment of portal hypertension