Résumé
Polyglandular autoimmunity (PGA) type 2 presenting in childhood is extremely rare. We report a case of type 2 PGA who had hypothyroidism, followed by diabetic ketoacidosis and was later diagnosed to have adrenal insufficiency also.
Sujets)
Adolescent , Diabète de type 2/complications , Humains , Polyendocrinopathies auto-immunes/complicationsRésumé
The etiology of slipped capital femoral epiphysis (SCFE) is unknown, though hormonal as well as mechanical factors have been implicated. We report a case of gigantism who presented with SCFE. This case provides an insight into the genesis of SCFE, which in this case was related to growth hormone excess and sex-hormone deficiency.
Sujets)
Adulte , Constitution physique , Épiphysiolyse/étiologie , Tête du fémur/imagerie diagnostique , Gigantisme/complications , Hormones sexuelles stéroïdiennes/déficit , Troubles de la croissance/complications , Hormone de croissance/effets indésirables , Humains , Fixateurs internes , MâleRésumé
Hyperthyroidism is seen in 3.5-26% of acromegalic subjects, and can occur through TSH-dependent or independent mechanisms. Thyrotoxicosis as the first presenting illness in acromegaly is particularly uncommon, as described in this patient who had both acromegaly and a toxic thyroid adenoma.