Résumé
Introduction: Vitiligo patients resistant to medical therapy pose a therapeutic problem to physicians. There are various surgical procedures for correcting stable vitiligo
Aim of work: To evaluate the efficacy of small [2-mm] punches minigraft therapy in relation to the patient age, disease site, subtype and the duration of stability of vitiligo
Patients and Methods: We used disposable 2.0-mm punch apparatus to perform minigraft therapy in 50 patients with different age range groups. Patients had either geheralized, segmental or local vitiligo, at variable sites. The duration of stability of vitiligo was different among studied patients
Results: Grading of repigmentation was assessed in relation to the age range with better results obtained in younger population [<20 years]. As regards the site of lesion, the face showed the statistically significant higher percentage of excellent response [88.89%] [P<0.05]. Segmental type of vitiligo was found to yield the best results. A significant positive correlation was detected between repigmentation score and the duration of stability of vitiligo [r=0.234, P<0. 05]
Conclusion: Age <20 years old, site of vitiligo patches, segmental subtype and longer duration of stability have positive influence on results of minigraft in patients with long standing vitiligo