Résumé
This study aims to establish normal values for nucleated red blood cells [NRBCs] in healthy, term, singleton neonates and to evaluate the association between some medical and obstetrical conditions, known to be associated with chronic hypoxia, and NRBC count elevation. We prospectively collected umbilical cord blood from 349 live bom, term, singletons, Delivered at our department. Cord blood was analyzed for nucleated RBC. We reviewed the medical record for maternal data and neonatal outcomes of gestations of>. 37weeks duration. The cases were divided into two main groups on the basis of the presence or absence of complicated pregnancies. The mean value for NRBCs per 100 WBCs in control group [those with uncomplicated pregnancies] was 2.4, the SD was 2.1, and the range was 0 to 10. There was significant elevation of NRBCs in cases of small for gestational age. And in cases complicated by maternal diabetes or pre-eclampsia [p< 0.05]. The value did not vary by maternal smoking. Apgar score showed trend toward inverse proportionality to the number of NRBCs. The NRBCs counts in the healthy, term neonates were in the range of 0-10. Elevated NRBC count was associated with states of relative hypoxia such as intrauterine growth restriction, maternal diabetes andpreeclampsia. Elevated NRBC count were also associated with lower Apgar scores
Résumé
To determine whether advanced placental calcification is associated with impaired placental function by assessment of different grades of placental calcification in relation to cord blood NRBCs count, a marker for chronic hypoxia. Nucleated Red Blood Cells [NRBCs] from cord blood of 200 singleton term non -asphyxiated neonates were compared with cord blood NRBCs of 51 term singletons proved to have 2ed and 3ed Grade placental calcification by ultrasound examination Foetal weight and Apgar score were also assessed in different groups. Grade III placental calcification [n=30] was not associated with a significant difference in NRBC counts compared to group one [n=200]: mean 2.45.S.D.2.4I and mean 2.40, SD 2.12 respectively [P> 0.8]. These result illustrated that advanced grades of placental calcification dose not Jeopardize fetal oxygenation, as evidenced by the non significant finding of NRBC counts in different groups, and the non Significant difference in fetal out come by comparing fetal weigh and Apgar scores for different groups
Résumé
Currently the only method in common use to assist the clinician in making Judgment is the ripeness of the cervix. Quantitatively this is expressed by the Bishop score, which is subjective and vary considerably among examiners, while transvaginal ultrasonographic cervical length measurement could represent a more accurate assessment of cervical effacement than digital examination. To compare transvaginal cervical length measurement and the Bishop score as predictors of duration of induction and successful induction resulting in vaginal delivery at term. Cross sectional, prospective study on a group of 70 women with singleton gestations scheduled for induction at >/= 37 weeks were studied. Transvaginal ultrasonographic measurement of cervical length was performed and the Bishop score was determined digitally. All labors were induced by continuous Oxytocin infusion and amniotomy performed when the head engaged and labor had become well established and cervix permitted. Vaginal delivery occurred in 52 [74.3%] of patient. Both Bishop score and transvaginal cervical length showed a linear correlation with duration of labor. Women with cervical length < 3 cm had shorter labor and were more likely to be delivered vaginally than those with cervical length >/= 3 cm, and women with Bishop score > 4 also had shorter labor and were more likely to be delivered vaginally. Ultrasonographically measured cervical length can be an added diagnostic tool for evaluation of successful induction of labor and duration of induction and is less subjective than Bishop score