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Ann. hepatol ; Ann. hepatol;16(1): 157-159, Jan.-Feb. 2017. graf
Article de Anglais | LILACS | ID: biblio-838098

RÉSUMÉ

Abstract: Lymphoepithelioma-like hepatocellular carcinoma (LEL-HCC) is a rare primary hepatic neoplasm with female predominance and relatively good prognosis. We report a 73-year-old female with chronic hepatitis B who developed metastatic lesions 5 years after underwent resection for LEL-HCC. The metastatic lesions showed a spectrum of morphologic findings, which could be mistaken for other entities such as lymphoma, particularly in lesions with single-cell infiltrative pattern and abundant tumor-infiltrating lymphocytes. Immunohistochemical study to confirm the origin of the neoplastic cells is important to make the diagnosis. We also highlighted the clinicopathologic correlation and potential therapeutic implication of programmed death ligand-1 expression in LEL-HCC.


Sujet(s)
Humains , Femelle , Sujet âgé , Marqueurs biologiques tumoraux/analyse , Carcinome hépatocellulaire/composition chimique , Antigène CD274/analyse , Tumeurs du foie/composition chimique , Biopsie , Immunohistochimie , Valeur prédictive des tests , Carcinome hépatocellulaire/secondaire , Carcinome hépatocellulaire/thérapie , Carcinome hépatocellulaire/virologie , Hépatite B chronique/complications , Tumeurs du foie/anatomopathologie , Tumeurs du foie/thérapie , Tumeurs du foie/virologie , Métastase lymphatique
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