Focusing on the regulation of epigenetic modification on retinal vascular disease / 中华眼底病杂志

Epigenetics has been very hot in the research of biomedicine. In addition to genetic factors, the occurrence of a disease is also influenced by environmental factors. Retinal vascular diseases are a type of irreversible blind eye disease, such as age-related macular degeneration and diabetic retinopathy. The retinal vessel changes are the major features of retinal vascular diseases, which are the result of interaction of multiple environmental factors and genes. Epigenetic modification mainly includes DNA methylation, histone modification, and non-coding RNA regulation. Epigenetic mechanisms mediate the effects of environmental factors on genes related to retinal vascular diseases, and affect the eventual development of the diseases. Therefore, ophthalmologists should keep eyes close on the role of epigenetics in retinal vascular diseases, track the progress of epigenetic methods in the treatment of retinal vascular diseases, and pay attention to the application prospects of epigenetics. Finding the epigenetic regulators of these diseases can not only deepen the understanding of the pathological mechanism of these diseases, but also provide new ideas for the diagnosis and treatment of these diseases.

Mental experience of nurses from outpatient department in dealing with patient's complaints: a qualitative study / 现代临床护理

Objective To study the mental experience of nurses from outpatient department in dealing with patient's complaints.Method Using convenient sampling method,15 nurses from 5 sections of the outpatient department were chosen as interviewees,with the interviews on their mental experience in handling the complaints from outpatients.Result The issues from the interviews included:part of the patients were unable to complain accurately,part of the nurses were ineffective and therefore inactive in handling the complaints;some of the nurses were poor at employing communication skills and some others were incapable of specifying the complaints or asking for assistance.Conclusions Complaint handling is part of the nurses' job in the outpatient service.The nurses should take the initiative to improve their ability in complaint handling,so as to handle the complaints in a positive and effective way and improve patient's satisfaction.

Survey and Analysis of Chinese Traditional Medicine Prescriptions in 2006 in Our Hospital / 中国药房

OBJECTIVE:To investigate the writing quality of Chinese traditional medicine prescriptions and the medication status in our hospital to promote standard prescription writing and rational administration.METHODS:A total of 11 018 Chinese traditional medicine prescriptions were randomly sampled from outpatient dispensary of traditional Chinese medicine in our hospital in 2006 to find out the non-standard and irrational prescriptions with age and sex,clinical diagnosis,dosage form,specification,usage,and the consumption sum of drugs as main indexes.RESULTS:Of the total Chinese traditional medicine prescriptions,27.85%(3 068)were non-standard in writing,of which,0.47% were without items of age and sex,5.59% without clinical diagnosis,2.72% without dosage form,1.39% without usage,23.64% were unclear in specification and dosage;the prescriptions in which only one drug was prescribed accounted for 90.86%;30.51% were prescriptions for special group;and 5.92% had a prescription consumption sum of no less than 200 yuan(≥200 yuan).CONCLUSION:The quality of Chinese traditional medicine prescriptions in our hospital remains to be further improved.