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Objective:To explore the application effect of dyadic intervention scheme based on dyadic disease management theory and Information, Knowledge, Attitude, and Practice model in the discharge preparation of elderly stroke patients and family caregivers.Methods:The 92 pairs of elderly stroke patients and their caregivers hospitalized in the Department of Neurology in People′s Hospital of Zhengzhou University were conveniently selected. The non synchronous control method quasi experimental research was adopted. Totally 46 pairs of subjects who met the criteria for admission and discharge from May to July 2022 were set as the control group, and routine nursing was carried out; from August to October 2022, 46 pairs of subjects who met the criteria for admission and emission were set as the observation group to implement the dyadic intervention program. The scores of discharge readiness, self-efficacy and unplanned readmission rate of patients between the two groups were compared, and the scores of caregiver readiness, self-efficacy and caregiver stress between the two groups were compared.Results:Finally, 85 pairs of subjects completed the study, with 42 pairs in the control group and 43 pairs in the observation group. On discharge day, the total scores of discharge readiness and caregiver readiness in the observation group were (95.19 ± 4.47), (23.02 ± 2.20) points, respectively, which were higher than those in the control group (85.71 ± 5.31), (19.57 ± 1.65) points, with statistically significant differences ( t=8.91,8.16, both P<0.01); the self-efficacy levels of patients in the observation group at discharge and one month after discharge, as well as those of caregivers at discharge and one month after discharge were (73.86 ± 4.87), (75.91 ± 4.51), (75.67 ± 4.99), (79.21 ± 4.90) points, respectively, higher than those in the control group (71.62 ± 5.19), (73.33 ± 4.91), (73.48 ± 4.24), (75.48 ± 4.24) points, with statistically significant differences ( t values were from 2.05 to 3.75, all P<0.05); the pressure levels of caregivers in the observation group at discharge and one month after discharge were (7.51 ± 2.48), (6.28 ± 1.99) points, respectively, lower than those in the control group (8.76 ± 2.55), (7.45 ± 2.36) points, with statistically significant differences ( t=-2.29, -2.48, both P<0.05); the unplanned readmission rate of patients in the observation group one month after discharge was 7.0% (3/43), lower than the control group′s 23.8% (10/42), with statistically significant difference ( χ2=4.65, P<0.05). Conclusions:The implementation of dyadic intervention on elderly stroke patients and caregivers can make their discharge preparation process more adequate, thus reducing the caregiver′s care pressure, reducing the unplanned readmission rate of patients, and improving their health outcomes.
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Objective To investigate the changes of serum immunoglobulin IgG in peripheral blood of infants aged 0-6 months,and to compare the effects of breast feeding and artificial feeding on the immune function of infants. Methods A total of 90 neonates born from January 2016 to December 2016 were divided into three groups: breast feeding group, mixed feeding group and artificial feeding group. There were 30 newborns in each group.Peripheral blood samples were collected at postnatal 1 d,3 d,7 d, 14 d, 42 d, 3 months and 6 months respectively. Serum levels of IgG were determined by radioimmunoassay, and the contents of each group were compared. T lymphocyte subsets(CD3+, CD4+, CD8+)in peripheral blood at postnatal 6 months were detected. Results The content of IgG in serum of neonatal decreased gradually with the increase of postnatal days.The serum IgG content at postnatal 14 d in the breast feeding group, the mixed feeding group and the artificial feeding group was (95.14 ± 4.55), (90.89±4.35),(91.74±4.19)mg/L respectively,and the breast feeding group was significantly higher than the other two groups,the difference among the groups was statistically significant(F=7.965,P<0.05).The CD8+T lymphocyte cells in the breast feeding group, the mixed feeding group and the artificial feeding group was 0.389 4±0.060 1,0.294 2±0.062 6,0.308 4±0.071 6 respectively,and the breast feeding group was significantly higher than the mixed feeding group and the artificial feeding group,and the difference among the groups was statistically significant(F=4.941,P<0.05).Conclusions Breast feeding can reduce the serum IgG content of infant consumption,slowing the pace of decline,effectively improve the infant's own ability to synthesize IgG,so as to improve infant immunity,promote their healthy growth,it is worthy of clinical application.
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Objective:To investigate the acceptance of disability for ischemic stroke patients and its related factors, in order to provide a theoretical basis on rehabilitation intervention in ischemic stroke patients with mental disability. Methods: A total of 180 patients with ischemic stroke were recruited. The Adaptation of Disability Scale-Revised (ADS-R), Medical Outcomes Study Social Support Survey (MOS-SSS), Herth Hope Inder (HHI) and Patient Health Questionnaire-9 (PHQ-9) were used to evaluate the patients. Results: The mean score of acceptance of disability was (88.2 ± 14.3) in ischemic patients. Multiple stepwise regressions indicated that the religion, education, MOS-SSS scores and HHI scores were positively associated with ADS-R scores(b'=0.33, 0.21, 0.30, 0.15). The medical insurance, disability(MRS) and PHQ-9 scores were negatively associated with ADS-R scores(b'=-0.16, -1.53, -0.43). Conclusion: The acceptance of disability in patients with ischemic stroke may be at a low level. The religion, education, medical insurance, disability, social support, hope level and depression may be related to the adaptation of disability.
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OBJECTIVE:To study the chemical compositions of n-butabol extract from Solanum lyratum. METHODS:Glucan LH-20 column chromatography,silica gel column chromatography and TLC were adopted to separate and purity the chemical com-positions,physicochemical property and spectral evidence to identify their structures. RESULTS:Totally 10 chemical compositions were separated from n-butabol extract,namely apigenin-7-O-β-D-apiofuanosyl(1→2)-β-D-glucose (1),apigenin-7-O-β-D-glucose (2),adenosine(3),3-methoxy-4-hydroxy-5-[(8′S)-3′-methoxy-4′-hydroxyl-phenyl-alcohol]-E-cinnamic-phenylpropyl alcohol-4-O-β-D-glucoside (4),N-(4-amino-butyl)-3-(3-hydroxy-4-methoxy-phenyl)-E-acrylamide (5),N-(4-amino-butyl)-3-(3-hydroxy-4-me-thoxy-phenyl)-Z-acrylamide (6),resveratrol (7),naringenin (8),quercetin (9) and dioscin (10). CONCLUSIONS:Compound 1-8 are first separated from S. lyratum,the study can lay a foundation for quality evaluation of S. Lyratum.
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Objective To investigate the level and influencing factors of caregivers′burden among primary caregivers of elderly stroke patients. Methods Totally 298 caregivers of elderly stroke patients were investigated with Zarit Burden Interview (ZBI), Hospital Anxiety and Depression Scale (HADS) and Simplified Coping Style Questionnaire(SCSQ). The patients were investigated with Modified Barthel Index (MBI). Results The caregivers′burden was in the mild level with a total score of 35.21±11.45. The influencing factors were the number of days of care, daily caring hours, hospital anxiety and depression score, the coping style and the ability of patients to perform ADL. Conclusions The primary caregivers of stroke patients have mild burden. The nurses should be synchronized to assess the health of patients and primary caregivers at the same time, understand the caregivers′burden, and provide specific care advice, in order to reduce the burden of their carer, so as to improve the quality of patients′life.
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Objective Our purpose is to investigate the expression of natriuretic peptide receptor A (NPR-A) in the retina and to understand the NPR-A’ s functions during the mouse development .Methods Mice eyes were harvested from E16 ( embryonic day 16 ) to P90 ( postnatal day 90 ) . Total of 127 eyes were used in the study . Immunohistochemistries of NPR-A were carried out .Results During development , NPR-A was widely expressed in the retinal neurons .In the outer nuclear layer , NPR-A began to appear in the inner and outer projections of cone and rod cells at P7, but decreased at P14.From P30 afterward, it continued to express weakly .In the inner nuclear layer , NPR-A expressed in the dendrites of bipolar cells weakly from P 7 to adulthood , whereas no expression in horizontal cells .In the ganglion cell layer, NPR-A started highly to express in the ganglion cell bodies at E 16, and in the meantime, in the nerve fiber layer , ganglion cell axons , NPR-A was expressed highly from embryonic to adult .In the inner and outer plexiform layers, NPR-A was highly expressed at P14, but decreased gradually after P30.In addition, NPR-A also widely expressed in the inner protrusions of Müller cells.Conclusion NPR-A participates in the development of the retina , and may be the key molecule in the developing retinal neurons .Moreover, it plays an important regulatory role in the functional activity of Müller cells .
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Objective To constmct the training system of specialized nurses in operation room.Methods The Delphi method was used to organize two rounds of consultations by 20 experts from July 1st to Nov.1st 2012.Results In the two rounds of expert consultations,experts' positive coefficients were 95％ and 100％,the authoritative coefficients of experts were 0.86 and 0.89.The evaluation system included 10 first level entries and 38 second-level entries,all entries' importance assignment was more than 4.0,all variable coefficients were less than 0.25.Conclusions The positivity and authority of experts in this study were in high degree,the concentration and harmonization of experts' opinions were relatively high,all entries' weight were relatively high.So the system has high scientific nature and reliability to provide a theoretical basis for specialized nurses in operation room.
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Objective To construct an index system of the performance appraisal to clinic nurses.Methods According to the BSC,KPI and SMART principal,we constructed the primary evaluation indexes.And then two rounds of Delphi consultation were conducted.Results An index system of the performance appraisal to clinic nurses was composed of 5 level-1 indexes,including 22 indexes.Conclusions The index system has high scientific nature and reliability to provide a theoretical basis for the performance appraisal to clinic nurses.
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@#ObjectiveTo investigate the relation between erectile dysfunction and myocardial infarction in recurrent myocardial infarction, sudden cardiac death and heart failure.Methods53 male patients with myocardial infarction were randomly divided into erectile dysfunction group and erectile normal group through International Index of Erectile Function-5(IIEF-5) subject test. Then the incidence of recurrent myocardial infarction, sudden cardiac death and heart failure were observed.ResultsThe incidence of recurrent myocardial infarction, sudden cardiac death and heart failure was higher in erectile dysfunction group than in erectile normal group.ConclusionThe prognosis of the patients with myocardial infarction following erectile dysfunction is unfavourable.