[Hemoglobinosis O-Arab: about three cases of incidental discovery during HbA1c assay at the biochemistry-toxicology laboratory of HMIMV in Rabat]

O-Arab hemoglobin, a rare variant of Hb related to a mutation in the HbA beta chain, is asymptomatic hemoglobinopathy in the heterozygous state and is well tolerated in the homozygous state. However, double heterozygosity or heterozygous composite can be in a severe clinical form hence the importance of diagnosis, both in genetic counseling and early management of patients. We report three cases of O-Arab heterozygous haemoglobinopathy discovered incidentally in the HbA1c assay by HPLC on ADAMS [Arkray®]