[Fructosamine and glycated hemoglobin level in pregnant women with abnormal glucose challenge test]

Gestational diabetes is affected 3-12% of women and occurs at the final stage of second trimester. This study was done to determine the fructosamine and glycated hemoglobin level in pregnant women with abnormal glucose challenge test. This case - control study was carried out on 96 pregnant women with glucose challenge test [GCT]>140 mg/dl as cases and 96 pregnant women with GCT<140 mg/dl as controls. The serum fructosamine and glycated hemoglobin determined using ELISA and chemical methods, respectively. In pregnant woman with abnormal GCT, there was a significant correlation with glycated hemoglobin and fructosamine. The glycated hemoglobin correlation was more significant compared to fructosamine [0.63 to 0.24]. There was not significant correlation between GCT with fructosamine and glycated hemoglobin in individuals with normal GCT. The measurement of glycated hemoglobin is more accurate than fructosamine in pregnant women with abnormal glucose challenge test

comparison of serum vitamin d level in patients with iron deficiency anemia and minor thalassemia

Of the most common hypochromic microcytic anemia are iron deficiency anemia and minor thalassemia, which are common in Iran and their differential diagnosis is extremely important. The level of 25-hydroxy vitamin D is the indication of vitamin D blood status. The aim of this study was to compare serum levels of vitamin D in people with minor thalassemia and iron deficiency anemia with healthy subjects in order to investigate the relationship between vitamin D deficiency and iron absorption. In this case-control study, 24 patients with minor thalassemia, 20 patients with iron deficiency anemia and 24 healthy individuals participated. Groups were matched for age and sex. Testing of Vitamin D level by ELISA, ferritin by quantitative luminescence method and HbA2 by column chromatography was carried out. The number of individuals with low level of vitamin D in iron deficiency group is 15 [75%], in minor thalassemia group is 8 [33/3%] and in the control group 11[45.8%]. In this study, the highest percentage of vitamin D deficiency is observed in cases with iron deficiency anemia. Because of association between vitamin D and anemia, iron and vitamin D supplementation is recommended to enrich the diet