Effect of adrenaline and ATP on glycerinated skeletal muscle

Glycerinated psose muscles of rabbit were used to study the effect of adrenaline and ATP on the contractile machinery of skeletal muscle. The muscles were placed in pure glcerine for 22 days to rupture all the membranes and then a few fibres were stripped off. The tension was recorded with the help of a highly sensitive force transducer in the presence of adrenaline and ATP. The results obtained showed a 19% higher tension generated in the presence of adrenaline and this increase in tension was significant statistically. Since the muscles used were devoid of their membranes and electrical potentials, it was assumed that drug produced higher tension by acting directly on the contracticle proteins themselves

Evaluation of the results of staged flexor tendon reconstruction

Twenty-one fingers in 19 patients were treated by a two-staged flexor tendon reconstruction. All injuries were in [no man's land] and both superficialis and profundus tendons were severed. The digits were evaluated 6 months or longer after stage-II surgery. The result were graded by comparing the preoperative passive motions of the metacarpophalangeal, proximal interphalangeal and distal interphalangeal joints after stage-I to the active motions of the same joints after stage-II. Overall end results were 19% excellent, 38.1% good, 23.9% fair and 19% poir. The result were affected by the patient age, severity of the injury, infection, adhesion and degree of flexion deformity prior to stage II. Complications included synovitis in 14.3%, infection in 9.5%, rupture of the tendon graft in 9.5% and adhesions after tendon grafting in 23.8%, This study revealed that staged tendon reconstruction is a useful method for restoration of digital function in flexor tendon injury with a badly scarred tendon bed

Prospective clinical and electrophysiological studies before and after anterior transposition of the ulnar nerve

Clinical and electrophysiological studies were performed for 41 patients [43 elbows] with tardy ulnar neuritis before and after subcutaneous anterior transposition of the ulnar nerve, with an average of 15 +/- 9.8 months follow up. Multiple mechanical causes for neuropathy were identified. Subjective improvement after the operation was obtained in more than 80% of the cases. The chance of recovery after the operation was greatly affected by preoperative symptoms period and the pathology which was present in the ulnar nerve and/or in the elbow, but seemed to be independent of the patient age