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Indian J Exp Biol ; 2001 Jan; 39(1): 57-62
Article Dans Anglais | IMSEAR | ID: sea-57437

Résumé

Uranyl nitrate inhibited root growth of Allium cepa at > or = 25 microM concentration. Fluorimetric analysis of metal uptake indicated the entry and accumulation of uranium into the root cell. Uranyl nitrate was neither clastogenic nor aneugenic as it failed to induce micronuclei significantly, but between 25 and 100 microM concentration, it increased significantly the frequency of sister chromatid exchange over that of control, implying its genotoxicity that possibly interfered with DNA replication and/or repair process.


Sujets)
Allium/effets des médicaments et des substances chimiques , Tests de micronucleus , Mutagènes/toxicité , Échange de chromatides soeurs , Nitrate d'uranyle/toxicité
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