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China Journal of Chinese Materia Medica ; (24): 274-280, 2018.
Article Dans Chinois | WPRIM | ID: wpr-776391

Résumé

With the completion of the human genome project, people have gradually recognized that the functions of the biological system are fulfilled through network-type interaction between genes, proteins and small molecules, while complex diseases are caused by the imbalance of biological processes due to a number of gene expression disorders. These have contributed to the rise of the concept of the "multi-target" drug discovery. Treatment and diagnosis of traditional Chinese medicine are based on holism and syndrome differentiation. At the molecular level, traditional Chinese medicine is characterized by multi-component and multi-target prescriptions, which is expected to provide a reference for the development of multi-target drugs. This paper reviews the application of network biology in traditional Chinese medicine in six aspects, in expectation to provide a reference to the modernized study of traditional Chinese medicine.


Sujets)
Humains , Découverte de médicament , Médicaments issus de plantes chinoises , Médecine traditionnelle chinoise , Biologie des systèmes
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