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1.
Rev. méd. Chile ; 145(9): 1122-1128, set. 2017. tab, graf
Article Dans Espagnol | LILACS | ID: biblio-902596

Résumé

Background: Moral competence (MC) in physicians is fundamental, given the increasing complexity of medicine. The "Moral Competence Test" (MCT © Lind) evaluates this feature and its indicator is the C Index (CI). Aim: To explore moral competence and its associated factors among physicians working in Chile. Material and Methods: The MCT was answered by 236 physicians from two medical centers who voluntarily participated in the study. Besides the test, participants completed an encrypted form giving information about gender, years in practice and post-graduate studies. Results: The average CI value of the participants was 20,9. Post-graduate studies had a significant positive influence on CI. There was a significant decrease in CI, between 16 and 20 years of professional exercise. Gender and the area of post-graduate studies did not have a significant influence. Conclusions: The studied physicians showed a wide range of CI which was positively affected by the postgraduate studies performed. The years of professional practice had a negative influence. Expanding training opportunities during professional practice could have a positive effect on CM as measured by CI.


Sujets)
Humains , Mâle , Femelle , Compétence professionnelle/statistiques et données numériques , Développement moral , Jugement moral rétrospectif , Personnel médical hospitalier/éthique , Pratique professionnelle/éthique , Valeurs de référence , Facteurs temps , Chili , Facteurs sexuels , Études transversales , Enquêtes et questionnaires , Analyse de variance , Répartition par sexe , Enseignement médical
2.
Mem. Inst. Oswaldo Cruz ; 99(6): 651-656, Oct. 2004. ilus, tab
Article Dans Anglais | LILACS | ID: lil-387918

Résumé

There is no effective chemotherapy against diseases caused by Phytomonas sp., a plant trypanosomatid responsible for economic losses in major crops. We tested three triazolo-pyrimidine complexes [two with Pt(II), and another with Ru(III)] against promastigotes of Phytomonas sp. isolated from Euphorbia characias. The incorporation of radiolabelled precursors, ultrastructural alterations and changes in the pattern of metabolite excretion were examined. Different degrees of toxicity were found for each complex: the platinun compound showed an inhibition effect on nucleic acid synthesis, provoking alterations on the levels of mitochondria, nucleus and glycosomes. These results, together with others reported previously in our laboratory about the activity of pyrimidine derivatives, reflect the potential of these compounds as agents in the treatment of Phytomonas sp.


Sujets)
Animaux , Antiprotozoaires , Euphorbia , Trypanosomatina
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