Sujets)
Adulte , Clofazimine/usage thérapeutique , Maladies de la conjonctive/induit chimiquement , Dapsone/usage thérapeutique , Association de médicaments , Hémorragie oculaire/induit chimiquement , Humains , Antilépreux/effets indésirables , Lèpre interpolaire/traitement médicamenteux , Mâle , Hémorragie buccale/induit chimiquement , Purpura thrombopénique/induit chimiquement , Rifampicine/effets indésirablesRésumé
Serum lipids and lipoproteins were assessed in sixty leprosy and forty age and sex matched healthy controls. The study subjects included cases of LL with reactions, LL without reactions, BL with reactions, BL without reactions, BT and TT types of leprosy. The levels of serum phospholipids, triglycerides, total cholesterol, LDL and VLDL fractions were significantly decreased in leprosy patients compared to control subjects. The levels of serum HDL cholesterol and HDL fraction were significantly elevated in leprosy patients. Maximum elevation in serum HDL cholesterol level and HDL fraction and maximum reduction in the levels of serum phospholipids, triglycerides, total cholesterol and LDL and VLDL fractions were observed in lepromatous leprosy (LL) patients with reactions.