Practice of chronic disease management model in tertiary hospitals Based on the Internet + doctors as the center / 中华医学教育探索杂志

With the advent of the Internet era, the development of new technology brings new opportunities for chronic disease management. Through long-term observation research, a large number of literature review and clinical practice and thinking, we have built the chronic disease management model of tertiary hospital centered on internet + doctors, and applied it to the management of patients with chronic diseases such as hypertension, and achieved good results, so as to provide decision-making reference for the construction of chronic disease management model in China.

High-dose chemotherapy in patients with terminal malignant tumors supported by autologous peripheral blood stem cells transplantation / 中国医师杂志

Objective To observe the safety and effectiveness of high-dose chemotherapy(HDT) supported by autologous peripheral blood hematopoietic stem cells transplantation(APBHSCT) in the patients of terminal or relapsed malignant tumors.Methods The patients achieved CR or PR after 4 cycles of conventional salvage chemotherapy were divided into two groups randomly.26 patients in the research group were adapted APBHSC+HDC,50 patients in the control group were adapted 2～4 cycles of routine chemotherapy.Results In the research group,hematopoiesis was reconstructed in all patients,8 out of 17 patients who achieved PR after 4 cycles of conventional salvage chemotherapy turned into CR after APBHSC+HDC(CR rate 47.1%).In the control group,33 patients who achieved PR after 4 cycles of conventional salvage chemotherapy were still PR after 2～4 cycles of routine chemotherapy.The median survival period in the research group was 11 months,which was longer than the one in the control group.The survival rates of 2,3 and 4 years in the research group were evidently higher than the ones in the control group(P