Angiolymphoid hyperplasia with eosinophilia: improvement in a recurrent case with isotretinoin

Angiolymphoid hyperplasia with eosinophilia [ALHE], characterized by dermal and subcutaneous nodules in head and neck areas, is often very disfiguring. There are different modalities of treatment but surgery seems to be the best. We report a 31-year-old man with recurrent ALHE showing considerable improvement with isotretinoin

Kindler syndrome: 2 case reports from India

Kindler syndrome [KS] is a rare autosomal recessive genodermatosis. We report two cases of KS with classical clinical presentations involving skin and mucus membranes. Clinically, both patients had four major features of KS in the form of acral skin blistering, photosensitivity, progressive poikiloderma, and diffuse cutaneous atrophy. Case 1 had associated features in the form of urethral stenosis, skin fragility and palmoplantar keratoderma with extension of the scaling onto the flexor aspect of the wrist and loss of palmar creases. Case 2 had associated features in form of anal stenosis, oesophageal stenosis, skin fragility and palmoplantar keratoderma with loss of palmar creases. An Interesting finding in our report is that both cases have prominent telengectasia involving face and neck regions

Piebaldism and vitiligo in two brothers

Piebaldism is an autosomal dominant uncommon [<1 in 20,000] congenital pigmentary disorder. Depigmented patches are present since birth. They usually remain unchanged throughout life. Vitiligo is its closest differential diagnosis. We report a unique family in which these two dissimilar depigmentations, i.e. piebaldism and vitiligo [with nevus depigmentosus], were noted in two brothers. To the best of our knowledge, this is the first report of this presentation in the literature