Diterpenos isolados de Humirianthera ampla. Miers.

From Humirianthera ampla, Icacinaceae, were isolated a phthalate, lupeol, â-sitosterol, glycosyl- sitosterol, one known annonalide diterpene and two new diterpenes named Humirianthol and Acrenol. Humirianthol and Acrenol were determined by 1D and 2D NMR spectroscopic techniques to be 3 â, 20:14 â, 16-diepoxy-3 á, 15 á-dihydroxy-7-pimaren-19, 6 â-olide and 3 â, 20-epoxi-3 á, 15, 16-trihydroxy-7-pimaren-19, 6 â-olide, respectively. Acrenol has antimicrobial activity.