Chromosome anomalies in normal androgenized infertile males

Chromosome anomalies are known to play a role in human infertility. Chromosome analysis of 103 normal androgenized infertile azoospermic [97.1%] or oligospermic [2.9%] males revealed that the frequency of chromosomal abnormalities was 8.7%. Two patients [1.94%] had a 46,XX chromosome complement, one patient [0.97%] had a 45,X karyotype, two patients [1.94%] had a 45,XY,t[13;14][p11;q11] karyotype, one patient [0.97%] had a 46,XY,inv[9][p12;q13] chromosome constitution, two patients [1.94%] had a 46,XY,del[Y][q12] karyotype, and one patient [0.97%] had a 45X/46,X+marker the nature of which was not clarified