Familial Polyposis Coli / 대한소화기내시경학회지

Familial adenomatous polyposis(FAP) is the most oommon of the polyposis syndromes. It is characterized by multiple colorectal adenoma and a high occurrence rate of associated colonic adenocarcinoma in all untreated cases. FPC is inherited as antosomal dominant trait. During 20 years after diagnosis, adenocarcinoma occurs in more than 50% of patients. Clinically, surgical resection should be advised at the time of diagnosis in almost all cases, and acquainted with the potential risks to their children and advised to seek genetic counselling. we report three cases with familial adenomatous polyposis in family.