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Rev. méd. Chile ; 137(10): 1283-1290, oct. 2009. tab
Article Dans Espagnol | LILACS | ID: lil-534034

Résumé

Background: A National Consensus Guideline published in 2005 established the basis for the diagnostic, severity assessment and treatment of community acquired pneumonia (CAP) in the adult population. The compliance with pneumonia clinical guidelines has been associated to a reduction in hospital stay healthcare-related costs, morbidity and mortality. Aim To describe the management and outcome of non-severe CAP in hospitalized adult patients treated in a rural hospital, based on the national clinical guidelines. Patients and methods: Ninety six patients aged 74 ± 13 years (50 males) hospitalized with non-severe pneumonia (group 3) at a community-based primary care center between January 1, 2006, and March 31, 2007, were evaluated. Results: Eighty percent of patients had concomitant diseases such as hypertension in 49 percent, diabetes in 23 percent and chronic obstructive pulmonary disease in 18 percent. All were treated with a third generation cephalosporin (ceftriaxone 1-2 g/day TV) as empirical therapy. Only 9 percent of patients also received a macrolide. Early switch to oral antimicrobial therapy was successful in two third of cases. Mean hospital length of stay was 5.0 ± 2.5 days, and 30-day mortality was 6.3 percent. Conclusions: Following the recommendations of the national clinical guidelines, most of these patients had a favorable response to monotherapy with a B-lactam antimicrobial. Early switch therapy to oral antibiotic was effective and safe, reducing significantly hospital length of stay as compared to previous national clinical studies.


Sujets)
Adolescent , Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Femelle , Humains , Mâle , Adulte d'âge moyen , Jeune adulte , Adhésion aux directives , Immunocompétence , Pneumopathie infectieuse/traitement médicamenteux , Administration par voie orale , Antibactériens/usage thérapeutique , Céphalosporines/usage thérapeutique , Chili , Infections communautaires/traitement médicamenteux , Infections communautaires/mortalité , Calendrier d'administration des médicaments , Hôpitaux ruraux , Durée du séjour/statistiques et données numériques , Pneumopathie infectieuse/mortalité , Résultat thérapeutique , Jeune adulte , bêta-Lactamases/usage thérapeutique
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