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Article Dans Anglais | IMSEAR | ID: sea-95099

Résumé

With avaibility of newer immunosuppressive agents, incidence of acute graft rejection has decreased. Mycophenolate mofetil is one such new drug, now available in the Indian market It has been found to be useful in prevention and treatment of acute and chronic rejection after transplantation. Besides transplant it has been used successfully in primary and secondary glomerulopathies (e.g. SLE) and other autoimmune diseases. The drug is well tolerated with side effects limited mainly to gastrointestinal system in the form of epigastric pain, vomiting and diarrhoea.


Sujets)
Sujet âgé , Aire sous la courbe , Biodisponibilité , Enfant , Essais cliniques comme sujet , Interactions médicamenteuses , Rejet du greffon/prévention et contrôle , Période , Humains , Immunosuppresseurs/métabolisme , Transplantation rénale , Adulte d'âge moyen , Acide mycophénolique/analogues et dérivés , Distribution tissulaire
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