Résumé
Background: Ritalin [methylphenidate Methylphenidate] is an amphetamine used to treat ADHD, symptoms of Narcolepsy, and some people with depression. This study was to investigate the effect of Ritalin food on blood albumin and some liver enzymes
Materials and Methods: In this study, 40 male Wistar rats were randomized in groups [1 control group, and three experimental groups]. In the control group physiologic serum and in the experimental groups a dose of mercuric chloride infused into the peritoneal cavity for 30 days. The amount of Ritalin was 2.5 ml in 1[st] group, 5 ml in group 2, 10 ml group 3, every other day for 30 days. After the due date of the invoice for blood samples, were tested
Results: There was a significant difference in albumin levels in experimental groups compared to the control group and there was a significant decrease in the amount of liver transaminases; the experimental group compared to the control group
Conclusion: This study shows that Ritalin causes liver enzymes disrupt the balance and serum albumin levels were increased
Résumé
The rapid development of the mining and industry activities increased and many toxic metals in the environment of the earth's crust has been dissipated and has taken risks to human exposure, inhalation. Today evidence of many diseases associated with environmental factors harmful to repellent Bio systems is increasing gradually, The majority of these factors were man-made and the activities associated with heavy metals was a major threat for human health. Mercury has the most toxic non-radioactive element that was already known. The purpose of this study was to investigate the effect of mercuric chloride intra peritoneally on blood albumin and some liver enzymes. In this study, 30 male Wistar rats randomized selected into 6 groups [1 control group, and experimental groups of 1, 2, 3, 4, 5]. In control group adequate serum physiology, and in experimental groups a dose of mercuric chloride infused into peritoneal cavity for 7 days. The amount of mercuric chloride infused were 1 mg/kg in 1[st] group, 2 mg/kg in group 2, 5 mg/kg in group 3, 7 mg/kg in group 4, and 10 mg/kg in the fifth group every other day for 7 days. After the 7 days blood samples, were tested and analyzed. In this study, there was a significant relation between decrease in albumin levels in experimental groups compared to the control group and a there was significant relation increase in the amount of transaminases; SGOT and SGPT in the experimental group. This study showed that intra peritoneal injection of mercuric chloride causes the balance were increased, of liver enzymes and serum albumin levels