Résumé
Aims: The aim of the study is to find whether there is any relationship between glycated hemoglobin level and serum lipid profile in type 2 diabetes mellitus patients. Study Design: A total of 128 study participants were approached during a period 6 months of which 72 were confirmed cases of type-2 diabetes mellitus and remaining 56 were non- diabetic, and served as control subjects under the age group of 30-60 years. Methodology: Fasting blood samples were collected from all the subjects. Body Mass index (BMI) was calculated. Fasting plasma glucose, glycated hemoglobin (HbA1c) Total cholesterol (TC), triglyceride (TG) and High Density Lipoprotein (HDL) was measured using commercially available kits. Statistical analysis was performed by use o f SPSS version l6. Results: Plasma FBS level of diabetic group was significantly higher (p=0.001) than that of the non diabetic subjects as shown in table. TC, TG, LDL and VLDL were higher in diabetic group when compared to that of non-diabetic group, except for HDL which was lower in dian=betic group when compared to non-diabetic greoup. LDL was statistically significant between the non-diabetic and diabetic groups. HbA1c levels of both diabetic and non- diabetic groups showed a significant correlation with TG, HDL, LDL and VLDL (p<0.05) except for cholesterol. Conclusion: The findings of this study clearly indicate that HbA1c as a useful biomarker for long-term glycaemic control and also as a good predictor of lipid profile.
Résumé
Aim: The aim of this study is to investigate whether dental nanocomposite Filtek Z350 XT and Ceram X-duo can benefit from electron beam irradiation in order to achieve increased flexural strength Place and Duration of Study: Department of Conservative Dentistry and Endodontics, A. B. Shetty Memorial Institute of Dental Sciences, Nitte University, Deralakatte, Mangalore, India and Microtron Centre; Department of Physics Mangalore University; Mangalore, India between May 2011 to March 2014. Materials and Methods: Materials were prepared on rectangular bar shaped specimens of 25-×2-×2-mm according to ISO standard -4049. Electron beam irradiation dose selected for the study were 1KGy, 3KGy and 5KGy. In total, 48 specimens were fabricated and divided into 4 groups based on radiation dose group I (non-radiated), group II (1KGy), group III (3KGy), group IV (5KGy) with 12 specimens in each. After 24 hours, specimens were subjected to 3-point bend test on a universal uniaxial servo mechanical testing machine. Statistical Analysis: Performed using one way ANOVA and inter group comparisons were done using tukeys multiple comparision. ‘P’ value<0.05 was considered statistically significant. Results: Flexural strength of Filtex Z350 XT before radiation was170.89±9.07.Flexural strength of Filtex Z350 XT after irradiation with 1KGy, 3KGy and 5KGy was found to be 269.06±94.91, 326.53±54.74 and 377.64±74.5 respectively. P value statistically significant (P<0.0001). Flexural strength of Ceram X duo before radiation was120.14±7.12.Flexural strength of Ceram X duo after irradiation with 1KGy, 3KGy and 5KGy was found to be 206.27±76.38, 177.31±67.35 and 229.33±59.15 respectively. P value statistically significant (P<0.0001). Conclusion: It can be concluded that electron beam irradiation can be used as a tool to modify the present day dental materials for enhancing their mechanical properties.
Résumé
Aim: The aim of this study was to evaluate the cytotoxicity of three resin luting agents Rely X luting cement, Rely X luting 2 cement and Clearfil SA luting cement before and after electron beam irradiation. Materials and Methods: Growth and maintenance of cell cultures of human pulp cells was done in Dulbecco’s modified Eagle’s Medium (DMEM). The test samples were divided into two Categories: Irradiated Category and Non-radiated Category. Samples in Irradiated category were exposed to electron beam radiation at 200Gy. Three subgroups of radiated category and non radiated category were made. All the samples were subjected to MTT assay and spectrophotometric analysis and their cytotoxicity was assessed. Statistical analysis was done using t test. Results: Evaluation of Rely X luting Cement showed that radiated samples of powder, liquid and set cements showed decreased cell viability than non radiated samples. In Case of Rely X luting 2 cement, radiated samples showed increased cell viability for Paste A and Paste B samples. But in set material, irradiated samples showed decreased cell viability as compared to non radiated samples. For Clearfil SA luting Cement, Paste B showed increased cell viability for radiated samples. Paste A and Set cement of radiated samples showed decreased cell viability than non radiated samples. Conclusion: In the present study , the increased cytotoxicity of irradiated samples may be due to increase in the release of unbound monomers which may be due to chain breakage after irradiation and a reduction in the cytotoxicity which may be due to the cross linking of unbound monomers during irradiation.