3.0T MRI Multi-b-value Diffusion Weighted Imaging in the Differential Diagnosis of Female Pelvic Benign and Malignant Lesions / 中国医学影像学杂志

Purpose To explore the diagnostic value of double exponential model for pelvic lesions using 3.0T MRI for the diagnosis of pelvic lesion. Materials and Methods Fifty patients with pelvic lesions (30 benign cases and 20 malignant cases) underwent MR750-diffusion weighted imaging (DWI) scans, with b values of 0, 50, 300, 600, 800 and 1200 s/mm2, Functool-MADC software was used on AW 451 workstations for data processing, Slow ADC value, Fast ADC value, Standard ADC value, Fraction of fast ADC value were recorded and compared between benign and malignant lesions, and Standard ADC images were fused with axial T2 fat-suppressed images. Results Slow ADC values [(1.83±0.86)×10-3 mm2/s] and Standard ADC values [(1.79±0.78)×10-3 mm2/s] of benign lesions were larger than those of the malignant lesions [Slow ADC values:(1.05±0.31)×10-3 mm2/s;Standard ADC values:(1.13±0.39)×10-3 mm2/s] (t=3.90, 3.51;P<0.01), and the difference of Slow ADC value was largest between benign and malignant lesions. Slow ADC values of both benign and malignant lesions were significantly less than the Fast ADC values [benign:Slow ADC value=(1.83±0.86)×10-3 mm2/s, Fast ADC value=(16.95±8.63)×10-3 mm2/s; malignant: Slow ADC value=(1.05±0.31)×10-3 mm2/s, Fast ADC value=(15.12±9.90)×10-3 mm2/s] (t=-10.40,-6.29;P<0.01). Conclusion Double exponential decay model is capable of differentiating benign and malignant pelvic tumors, thus is of great significance for clinical preoperative diagnosis.

Study of Bingpeng oral paste / 中成药

Objective:To study new dosage form of Bingpeng powder referring to oversea patent. Methods: To disperse Bingpeng powder, adhesive and viscosity builders (such as gelatin, carboxymethylcellulose, hypromellose or carbomer), nonionic emulsifier (gluceryl monostearate) and white vaseline into liquid paraffin, stir to attain paste. The formulation was screened by adhesive strength, shape keeping characteristic and water asorbing value. Results: The better formulation: Bingpeng powder 5.0g, hypromellose 21.0g, carbomer 14g, gluceryl monostearate 3.0g, white vaseline 7.0g, liquid paraffin to 100.0g; the paste getting rabbits' artificial ulcers healed more quickly than powder does. Conclusion: The paste is applied more expediently and more effective for oral ulcer.