RÉSUMÉ
Background: Long-term use of denture causes significant changes in its supporting structures and can lead to constant pain and discomfort. Soft lining material extensively used in field of prosthodontics to improve fit of conventional acrylic resin denture for restoring optimal health of abused oral tissue showing degenerative change. Method: Specially designed metal mould used for fabrication of 80 acrylic resin blocks. Applying soft liner between 2 acrylic sample using metal mould and grouping these samples for immersion in solution of denture cleansers. These acrylic samples were then divided into 2 groups of 40 samples each for applying 2 variety of soft liner for each group (L1 and L2). Keeping specimen in solution of denture cleanser per day for 8 h keeping each specimen 3 times a day=equals to 3 days treatment. Thus, keeping the specimen for 30 days×3 exposure=amount to 90 days (3 months) exposure and then tensile bond strength measured using universal testing machine (Instron). ANOVA test is applied. Results: Tensile bond strength of Viscogel soft liner with acrylic based is decreased with more Polident denture cleanser followed by Efferdent, Clinsodent and least affected by water which is statistically significant. Conclusions: The clinician should choose denture cleanser by considering the microbiologic properties of cleansers and material aspects such as the compatibility of denture cleanser with soft liners.