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Rev. bras. cir. cardiovasc ; 32(6): 462-467, Nov.-Dec. 2017. tab, graf
Article Dans Anglais | LILACS | ID: biblio-897954

Résumé

Abstract Objective: The present study refers to a determination of the preoperative B-type natriuretic peptide is a predictor of short-term all-cause mortality in patients undergoing on-pump coronary artery bypass graft surgeries. Methods: Two hundred and twenty-one patients undergoing on-pump coronary artery bypass graft surgeries were evaluated prospectively during a 30-day postoperative follow-up period. Serum B-type natriuretic peptide concentration was measured without a 24-hour period prior to the surgical procedure and the value obtained was correlated with a short-term all-cause mortality. Results: Data analysis showed that all-cause mortality rates were equal to 9.5% in 30 days. Accuracy analysis by the receiver operating characteristic curve found an ideal cut-off value of B-type natriuretic peptide equal to 150 pg/mL in relation to mortality (AUC=0.82, 95% CI=0.71-0.87, P<0.001). Multivariate analysis showed that B-type natriuretic peptide value greater than or equal to 150 pg/mL (P=0.030, HR=3.99, 95% CI=1.14-13.98) was an independent predictor of all-cause mortality in a 30-day follow-up period. Conclusion: Preoperative serum B-type natriuretic peptide concentration is an independent predictor of short-term all-cause mortality in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass.


Sujets)
Humains , Mâle , Femelle , Adulte d'âge moyen , Sujet âgé , Pontage aortocoronarien/mortalité , Peptide natriurétique cérébral/sang , Brésil/épidémiologie , Marqueurs biologiques/sang , Taux de survie , Études prospectives , Facteurs de risque , Courbe ROC , Sensibilité et spécificité , Circulation extracorporelle , Période préopératoire
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