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Ann. hepatol ; 16(1): 149-156, Jan.-Feb. 2017. graf
Article Dans Anglais | LILACS | ID: biblio-838097

Résumé

Abstract: Introduction and aims. Liver resection is the treatment of choice for many primary and secondary liver diseases. Most studies in the elderly have reported resection of primary and secondary liver tumors, especially hepatocellular carcinoma and colorectal metastatic cancer. However, over the last two decades, hepatectomy has become safe and is now performed in the older population, implying a paradigm shift in the approach to these patients. Material and methods. We retrospectively evaluated the risk factors for postoperative complications in patients over 65 years of age in comparison with those under 65 years of age after liver resection (n = 360). The set comprised 127 patients older than 65 years (35%) and 233 patients younger than 65 years (65%). Results. In patients younger than 65 years, there was a significantly higher incidence of benign liver tumors (P = 0.0073); in those older than 65 years, there was a significantly higher incidence of metastasis of colorectal carcinoma to the liver (0.0058). In patients older tan 65 years, there were significantly more postoperative cardiovascular complications (P = 0.0028). Applying multivariate analysis, we did not identify any independent risk factors for postoperative complications. The 12-month survival was not significantly different (younger versus older patients), and the 5-year survival was significantly worse in older patients (P = 0.0454). Conclusion. In the case of liver resection, age should not be a contraindication. An individualized approach to the patient and multidisciplinary postoperative care are the important issues.


Sujets)
Humains , Adulte d'âge moyen , Sujet âgé , Sujet âgé de 80 ans ou plus , Complications postopératoires/épidémiologie , Ablation par cathéter/effets indésirables , Hépatectomie/effets indésirables , Tumeurs du foie/chirurgie , Complications postopératoires/diagnostic , Complications postopératoires/mortalité , Facteurs temps , Loi du khi-deux , Modèles des risques proportionnels , Incidence , Analyse multifactorielle , Études rétrospectives , Facteurs de risque , Facteurs âges , Résultat thérapeutique , Ablation par cathéter/mortalité , Slovaquie , Appréciation des risques , Sélection de patients , Estimation de Kaplan-Meier , Hépatectomie/méthodes , Hépatectomie/mortalité , Tumeurs du foie/mortalité , Tumeurs du foie/anatomopathologie
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