Effect of dietary phytoestrogen; genistein; an improvement of the immunity and other biochemical indices of alloxan-induced diabetic rats

This study was set performed to investigate the effect of feeding alloxan-induced diabetic rats with experimental diets containing genistein at different levels [2.5, 5.0, 10.0 and 20.0 mg/kg diet] on serum glucose level, lipid profile, immunoglobulins [IgG, IgM and IgA], T-lymphocytes CD+4 and CD+8, potential hepatic and renal antioxidant activity as well as body weight gain and daily food intake. The study concluded that dietary genistein displays a range of physiological functions, which may be of multiple health benefits in diabetes, as an inhibitor of intestinal glucose uptake and preventive agent for glucose-induced lipid peroxidation