Résumé
PURPOSE: Since 1996, the Korean Breast Cancer Society has collected nation-wide breast cancer data and analyzed the data using their online registration program biannually. The purpose of this study was to evaluate the characteristics of Korean breast cancer from 2008 and examine chronological based patterns. METHODS: Data were collected from 38 medical schools (67 hospitals), 20 general hospitals, and 10 private clinics. The data on the total number, gender, and age distribution were collected through a questionnaire as well as other detailed data analyzed via the online registration program. RESULTS: In 2008, there were 13,908 patients who were newly diagnosed with breast cancer. The crude incidence rate of female breast cancer was 57.3 among 100,000 and the median age was 49 years. The age distribution had not changed since the initial survey; however the proportion of postmenopausal patients had increased and median age was older than the past. In staging distribution, the proportion of early breast cancer (stage 0, I) was 47.2% with, breast-conserving surgery performed in 58% and mastectomy in 39.5%. CONCLUSION: Compared to past data, the incidence of breast cancer in Korea continues to rise. Furthermore, the proportion of those detected by screening and breast conservation surgery has increased remarkably. To understand the patterns of Korean breast cancer, the nation-wide data should continuously investigated.
Sujets)
Femelle , Humains , Répartition par âge , Région mammaire , Tumeurs du sein , Hôpitaux généraux , Incidence , Corée , Dépistage de masse , Mastectomie , Mastectomie partielle , Systèmes en direct , Enregistrements , Écoles de médecine , Enquêtes et questionnairesRésumé
Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system and its lesions are multiple in time as well as space.We experienced a case of a 14-year-old-girl with dysphagia, paresthesia and headache. Brain MRI scans demonstrated high signal intensities on T2-weighted images at the medulla and upper cervical cord. Acute disseminated encephalomyelitis was diagnosed and methylprednisolone pulse therapy was done. After 6 months she re-experienced diplopia, ophthalmoplegia and other neurological symptoms. There were increased signal intensities on T2-weighted image at the tegmentum, periaqueduct and hypothalamus in follow-up brain MRI. Finally, a diagnosis of multiple sclerosis was made. Methylprednisolone pulse therapy was started and she then recovered without any neurologic symptoms and signs. We report a case of multiple sclerosis in a 14-year- old-girl who was confirmed by clinical courses and serial MRIs.
Sujets)
Encéphale , Système nerveux central , Troubles de la déglutition , Maladies démyélinisantes , Diagnostic , Diplopie , Encéphalomyélite aigüe disséminée , Études de suivi , Céphalée , Hypothalamus , Imagerie par résonance magnétique , Méthylprednisolone , Sclérose en plaques , Manifestations neurologiques , Ophtalmoplégie , ParesthésieRésumé
The virus-associated hemophagocytic syndrome is a disorder characterized by a benign, generalized histiocytic proliferation, with marked hemophagocytosis associated with systemic viral infections. We experienced a case of Epstein-Barr virus (EBV)-associated hemophagocytic syndrome in a 2-year-old female who admitted to our department of pediatrics because of high fever, abdominal distension. Evidence for acute, primary EBV infection was demonstrated with serological and in situ hybridization method. Her presentation, treatment, and clinical course are discussed.