Ultrasound Measurement of Korean Fetal Growth Parameters by Gestational Age in Midtrimester Pregnancy / 대한산부인과학회잡지

OBJECTIVE: This study was done to formulate Korean fetal biometry charts of midtrimester presenting percentile values as a function of gestational age. METHODS: The relationships between the ultrasound measurement of 5 fetal parameters (biparietal diameter, head circumference, abdominal circumference, femur length, transverse cerebellar diameter) and nuchal skinfold thickness and menstrual age were determined by a cross-sectional study. The study group consisted of 215 normal healthy pregnant Korean women with known last menstrual period and regular menstrual period who had been performed genetic amniocentesis at our hospital and for whom complete pregnancy outcome information was available. All ultrasound examination was performed by one expert examiner. For each of the 5 parameters, the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles were determined. RESULTS: Ready-to-use fetal measurement charts in midtrimester are presented in a format giving the percentile values as a function of gestational age. CONCLUSION: These fetal biometry charts, obtained from midtrimester, Korean women can be used as a reference value.

A Case of Strumal Carcinoid Tumor of the Ovary / 대한부인종양콜포스코피학회잡지

Strumal carcinoid of ovary is an unusual form of monodermal ovarian teratoma with thyroid-like follicles admixed with typical carcinoid tumor pattern. Most of them arise in dermoid cyst or in mature solid teratoma. Recently we experienced a case of strumal carcinoid postoperatively and report this case with a brief review of the concerned literatures.

A Case of Brain Metastases from Advanced Ovarian Cancer / 대한부인종양콜포스코피학회잡지

The incidence of brain metastasis from the ovarian cancer is increasing because of the increased survival rate of the ovarian cancer patients and new development of the diagnostic imaging study. The traditional treatment of the brain metastasis is whole brain radiation therapy and recent trend of the treatment is multidisciplinary treatment (radiation therapy, surgery, radiosurgery, and chemotherapy). Recently we experienced a case with multiple brain metastases from the ovarian cancer which were treated by a multimodality approach including gamma-knife radiosurgery. She was diagnosed as epithelial ovarian cancer, FIGO stage IIIc, and underwent 9 cycles of cisplatin based combination chemotherapy (cyclophospamide, THP, cisplatin) after optimal cytoreductive surgery with Hartmans operation. Complete remission was achieved, but multiple brain metastases were detected 56 months after the initial diagnosis of ovarian cancer. She had no recurrent lesion outside the brain, and underwent surgical resection of the one respectable lesion and then gamma-knife radiosurgery for another unresectable lesion. She remains in a disease-free state without any symptoms for 4 months. We report this case with a brief review of the concerned literatures.

Pregnancy associated with kyphoscoliosis / 대한산부인과학회잡지

OBJECTIVE: To assess the outcomes of pregnancies in women with kyphoscoliosis. METHOD: A total of 15 patients (17 pregnancies) complicated by kyphoscoliosis were reviewed among 19,717 deliveries between Jan. 1991 and Apr. 2001, from the Department of Obstetrics and Gynecology, Seoul National University Hospital. Their prenatal course, mode of deliveries, and pregnancy outcomes were scrutinizingly investigated. RESULTS: The incidence of kyphoscoliosis in this study was one per 1160 deliveries. The mean age of these patients in their pregnancies was 30.6+/-4.4 years (range 23-38), mean height 143.5+/-14.0 cm (range 124-160), and mean weight 55.8+/-14.4 kg (range 38-96). The causes of kyphoscoliosis included idiopathic (n=8), spinal tuberculosis (n=3), external trauma (n=3), poliomyelitis (n=1), spinal muscular atrophy (n=1), and progressive muscular dystrophy (n=1). The mean forced vital capacity (FVC) was 2.098+/-0.774 L (range 0.54-3.59) and mean vital capacity (VC) % predicted was 68.2+/-20.6% (range 24-105) prior to delivery. Vaginal delivery was performed in 4 cases, and cesarean section in 13. Fetal growth restriction was identified in 7 cases, and one case had both fetal heart anomaly and imperforate anus. Two babies were managed in neonatal intensive care unit; preterm birth at 34 weeks in one case, and term birth with low apgar score in the other. Maternal pulmonary complication was developed in two cases, the lowest two values of FVC and VC % predicted, one was FVC 0.86 L, VC % predicted 33% and the other was FVC 0.54L, VC % predicted 24%. These mothers were managed with transnasal oxygen therapy in one, artificial oxygen therapy in the other. CONCLUSION: The maternal and perinatal risks in pregnancy associated with kyphoscoliosis may be dependent on maternal pulmonary function prior to delivery.

Pregnancy associated with kyphoscoliosis / 대한산부인과학회잡지

OBJECTIVE: To assess the outcomes of pregnancies in women with kyphoscoliosis. METHOD: A total of 15 patients (17 pregnancies) complicated by kyphoscoliosis were reviewed among 19,717 deliveries between Jan. 1991 and Apr. 2001, from the Department of Obstetrics and Gynecology, Seoul National University Hospital. Their prenatal course, mode of deliveries, and pregnancy outcomes were scrutinizingly investigated. RESULTS: The incidence of kyphoscoliosis in this study was one per 1160 deliveries. The mean age of these patients in their pregnancies was 30.6+/-4.4 years (range 23-38), mean height 143.5+/-14.0 cm (range 124-160), and mean weight 55.8+/-14.4 kg (range 38-96). The causes of kyphoscoliosis included idiopathic (n=8), spinal tuberculosis (n=3), external trauma (n=3), poliomyelitis (n=1), spinal muscular atrophy (n=1), and progressive muscular dystrophy (n=1). The mean forced vital capacity (FVC) was 2.098+/-0.774 L (range 0.54-3.59) and mean vital capacity (VC) % predicted was 68.2+/-20.6% (range 24-105) prior to delivery. Vaginal delivery was performed in 4 cases, and cesarean section in 13. Fetal growth restriction was identified in 7 cases, and one case had both fetal heart anomaly and imperforate anus. Two babies were managed in neonatal intensive care unit; preterm birth at 34 weeks in one case, and term birth with low apgar score in the other. Maternal pulmonary complication was developed in two cases, the lowest two values of FVC and VC % predicted, one was FVC 0.86 L, VC % predicted 33% and the other was FVC 0.54L, VC % predicted 24%. These mothers were managed with transnasal oxygen therapy in one, artificial oxygen therapy in the other. CONCLUSION: The maternal and perinatal risks in pregnancy associated with kyphoscoliosis may be dependent on maternal pulmonary function prior to delivery.