Résumé
In 20 patients with psoriasis, 27 early psoriatic lesions of 1-2mm size (16 papules with scale and 11 maculopapules without scale) and 15 clinically uninvolved skin at distance of 2-4em from the nearest psoriatic lesion were histologically examined in an attempt to obtain information on the mechanism which initiates the development of the skin changes. (countinued..)
Sujets)
Humains , Psoriasis , PeauRésumé
We report two cases of hyperlipoproteinernia(HLP) with various cutaneous xanthomas. Case 1 was a 12-year-old girl, who had tuberous, tendinous, and plane cutaneous xanthomas and corneal arcus of the left eye. Case 2 was a 40-year-old man, who had tuberous, eruptive, and plane cutaneous xanthomas. Serum lipid and lipoprotein analysis reveoled patterns of Type IIa HLP in case 1 and, of Type IIb HLP, in case 2. They have been treated with diet control and hypolipidemic drugs and are under our continuing medical supervision.
Sujets)
Adulte , Enfant , Femelle , Humains , Hyperlipoprotéinémie de type II/diagnostic , Hyperlipoprotéinémie de type II/traitement médicamenteux , Hypolipémiants/usage thérapeutique , Lipoprotéines , Xanthomatose/diagnostic , Xanthomatose/traitement médicamenteuxRésumé
We report a case of bowenoid papulosis of the vulva in a 37-year-old woman. Bowenoid papulosis represents a new phenomenon which shows clinical characteristics quite different from classical Bowen's disease and histologic features of squamous cell carcinoma in situ. The patient had several brown-black flat papular lesions on the both sides of the vulva. The lesions were 2 to 9 mm in diameter, somewhat verrucoid and sharply demarcated. On history, these lesions developed from previous several grouped vesicular eruptions which were suspected to the lesions of herpes simplex. Although clinically the lesions appeared benigh, histologic examination showed. changes of squamous cell carcinoma in situ. The lesions were removed with electrodesiccation & curettage and are under observation. It is considered that bowenoid papuIosis should be ruled out by histologic examination in cases of unusual papular lesions of the genitalia in young people and that additional case studies with long-term folIow-up will be needed.