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1.
Southeast Asian J Trop Med Public Health ; 1999 Jun; 30(2): 265-8
Article Dans Anglais | IMSEAR | ID: sea-32036

Résumé

The prevalence of CMV antibody in various groups of Thai population was studied. Pregnant women and young children had been infected with CMV more than the other studied groups. Children of both sex had equal chance of getting CMV infection while the risk of CMV infection in adult between male and female was significantly difference (p < 0.001). Pregnant women had higher chance to get CMV infection than normal women. Prevalence of CMV antibody at present was similar to previous studies.


Sujets)
Adolescent , Adulte , Répartition par âge , Anticorps antiviraux/sang , Enfant , Enfant d'âge préscolaire , Infections à cytomégalovirus/épidémiologie , Femelle , Humains , Nourrisson , Nouveau-né , Mâle , Grossesse , Facteurs de risque , Études séroépidémiologiques , Thaïlande/épidémiologie
2.
Southeast Asian J Trop Med Public Health ; 1988 Dec; 19(4): 601-7
Article Dans Anglais | IMSEAR | ID: sea-31623

Résumé

It has already shown that catalase activity is significantly decreased in red cells of patients with P. falciparum. The mechanism suggested was by this enzyme inactivation through increased H2O2 generated during malarial infection. The present study was performed to verify this hypothesis. Catalase activities of red cells with high or low parasitemia in patients with P. falciparum were found to be lower than those of normal red cells. However, P. falciparum-infected red cells cultured for one week showed similar SOD and catalase levels to normal red cells. There was also no significant difference in the catalase levels between the parasitized and non-parasitized red cells. The difference in catalase activity of infected red cells before and after culture could be explained in terms of the activation of mononuclear cells and macrophages in vivo. During the sojourn of the parasitized red cells in close proximity to the macrophages of the spleen, they might trigger oxidative bursts resulting in increased H2O2. In order to protect themselves from oxidant damage, the catalase in the infected red cells could be inactivated by H2O2 resulting in the reduction of this enzyme.


Sujets)
Adulte , Animaux , Catalase/sang , Cellules cultivées , Érythrocytes/enzymologie , Femelle , Humains , Paludisme/sang , Mâle , Adulte d'âge moyen , Plasmodium falciparum/enzymologie , Rate/métabolisme , Superoxide dismutase/sang
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