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Pakistan Journal of Pharmaceutical Sciences. 2013; 26 (2): 251-254
Dans Anglais | IMEMR | ID: emr-193720

Résumé

This work aimed to evaluate the inhibitory effects of Olea ferruginea crude leaves extract that are commonly used as remedy to cure infections in the tribal [Khyber Agency] areas of Pakistan against some of bacterial and fungal pathogens. The crude n-hexane fraction was appreciably active against both gram positive and negative microorganisms [MIC ranged from 7.5 to 15 mg/ml] followed by butanol fraction [MIC 15 to 30 mg/ml]. Conversely least biological activity was shown by chloroform [30 mg/ml] and methanol [15 to 30 mg/ml] crude fractions. The MBC observed for all crude fractions was same or 2 times higher when compared with MIC for all crude extract fractions. Likewise all the fractions showed activity against Aspergillus niger and maximum zones of inhibition were shown by the n-hexane fraction [14+/-[0.02], butanol [13+/-[0.02] followed by methanol [9+/-[0.05] and chloroform fractions [7+/-[0.02]. These results clearly imitate the antibacterial and antifungal potential of Olea ferruginea and hence we recommend the whole plant for further futuristic studies

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