Résumé
Introduction: Thyroid hormones influence the haematologicalindices under physiological conditions. The exact causeof anemia in thyroid dysfunction is not clearly understood.The aim of this study was to investigate the changes in thehaematological parameters in hypothyroidism, subclinicalhypothyroidism and hyperthyroidism and the mechanismsunderlying it.Material and methods: The study was performed on69 cases of clinical hypothyroidism, 15 cases of clinicalhyperthyroidism, 6 cases of subclinical hypothyroidism and99 healthy individuals selected as the control group. Patientswere grouped as hypothyroid and hyperthyroid based on theTSH measurements (0.3-5.5µIU/mL) by Chemiluminescencemethod. Based on TSH levels (<0.3µIU/mL), patients werecategorized as hyperthyroidism and TSH levels (>5.5µIU/mL) as hypothyroidism. Hemoglobin and complete bloodcount which includes PCV, MCV, MCH, MCHC, RDW wereestimated. The results were analysed by SPSS software.Results: Analysis of the data obtained showed statisticallysignificant difference (p<0.05) in Hb, PCV, RDW betweenthyroid cases and controls. The difference was not significant(p>0.05) for MCV, MCH and MCHC.Conclusion: Thyroid hormones have to be evaluated in casesof refractory anemia not responding to iron supplementation.