Prevalence and genotype distribution of hepatitis B virus among migrant workers in Lombok Island, Indonesia

To examine the potential risk of hepatitis B virus (HBV) spread in Indonesia by migrant workers, based on the molecular characteristics of HBV strains. Methods: Sera collected from migrant workers traveling to their destination countries (pre-migrant workers) and those returning to Indonesia (post-migrant workers) were screened for HBsAg by ELISA, followed by HBV DNA detection by PCR and (sub) genotype/subtype determination according to surface region and whole genome sequencing. Results: Of 87 pre-migrant workers, 15 (17.24%) were HBsAgpositive, whereas 15 (12.10%) of 124 post-migrant workers were HBsAg seropositive. HBV genotype analysis based on the S region showed that HBV-B3/adw2 was predominant (96.15%, 25/26) whereas 3.85% (1/26) of isolates were HBV-C3/adrq+. Whole genome sequencing of selected strains and phylogenetic tree analysis identified subgenotype B7 in three samples previously categorized as subgenotype B3 based on S region analysis, supporting a recent argument that subgenotypes B5/B7/B8/B9 could be considered as a quasi-subgenotype of B3. Conclusions: A high prevalence of HBsAg carriers was detected among migrant workers from Lombok Island, with no significant difference in prevalence between before and after returning to Indonesia. All strains were classified into genotypes common in Indonesia, and the results suggested that migrant workers are not a risk factor for HBV transmission into Indonesia.

The Long-Term Psychological Impact of Ethnic Tension in Adolescents of the Solomon Islands / 国際保健医療

<b>Objective</b><br>The purpose of this study was to assess the psychological impact and associated factors in adolescents 5 years after the ethnic tension in the Solomon Islands. <br><b>Methods</b><br>In total, 199 high school students and villagers from Guadalcanal province and Malaita province participated in this study. To examine the psychological impact of the ethnic tension, a semi-structured interview was performed using a questionnaire and the Impact of Event Scale Revised (IES-R) for posttraumatic stress disorders (PTSD) symptoms. The participants were divided into three groups according to the places (A, B, C) where the participants lived at the beginning of the ethnic tension. <br><b>Results</b><br>Recalled emotions of traumatic experiences were significantly more severe in the most affected areas (group A, B). Although previous studies showed females are more emotionally impacted than males in disaster, the emotional impact was significantly more frequent in males than females in this study. Especially, the IES-R score was significantly higher in males of group A. No differences were found in the IES-R scores among the three groups; A: 33.4, B: 30.0, C: 34.5. The adolescents in this study had higher IES-R scores.<br><b>Conclusions</b><br>This study indicates that the PTSD symptoms of the adolescents have persisted for 5 years after the ethnic tension in the Solomon Islands.