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1.
Egyptian Journal of Biophysics and Biomedical Engineering. 2002; 3: 91-111
Dans Anglais | IMEMR | ID: emr-59184

Résumé

This present study was conducted to investigate some adverse effects due to microwave exposure as well as investigating the possible effects of acute exposure to radiation on liver and testicular tissues, antioxidant enzymes as superoxide dismutase and toxic free radical lipid peroxide that results from stress oxidative tissue damage as well as the effect of microwaves on some trace elements that act as metalloenzyme as zinc and copper. In this work, four groups of adult male albino rats were used. The first act as a control group, the second group was exposed to microwaves radiation 3 hr/day for seven days consecutively at a dose of 170mw/cm2.sec. and frequency of 2.06 GHz [acute exposure]. The third group was exposed to microwave radiations like the second group in addition to concomitant administration to propolis [10mg/kg b. wt. oral for 7 days] and the fourth group was exposed to microwave radiation like the second group in addition to concomitant administration to oral zinc sulphate [3.14 mg/kg b. wt. oral for 7 days]. After the last exposure, rats were treated with pentobarbital sodium and blood samples were taken by heart puncture for determination of alkaline phosphatase [ALP], alanine aminotransferase [ALT], testosterone and follicle stimulating hormone [FSH]. After blood collection, the animals were decapitated by cervical dislocation, testes and liver were histopathologically observed. Oxidative stress was examined by determination of lipid peroxidation [MDA] and measurement of Cu/Zn ratio


Sujets)
Animaux de laboratoire , Tests de la fonction hépatique , Testostérone/sang , Hormone folliculostimulante/sang , Foie/effets des radiations , Testicule/effets des radiations , Superoxide dismutase , Cuivre/sang , Zinc , Propolis , Animaux de laboratoire , Maladie aigüe , Rats
2.
Egyptian Journal of Biophysics and Biomedical Engineering. 2002; 3: 155-73
Dans Anglais | IMEMR | ID: emr-59187

Résumé

The objective of this study was the evaluation of the possible adverse effects of microwaves [e.g. mobile, microwave ovens, etc.] on some vasoactive substances as catecholamine [norepinephrine and epinephrine], 5 hydroxy tryptamine [serotonin] and histamine as well as histaminase enzyme activity and the possible role of Nigella sativa oil [NSO] administration in albino rats. Male adult albino rats were divided into control group [n=10], group II [n=10] received microwaves for 7 days consecutively at a dose of 170 mW/Cm2 and frequency of 2.06 GHz for 3 hours [acute group], the third group [group III] [n=10] received the same dose as group II but for 28 consecutive days [chronic group], the fourth group [group IV] was treated as group II with concomitant administration of Nigella sativa oil [NSO] 100 mg/kg/day/orally by gastric tube. The fifth group [n=10] was treated as group III with concomitant oral administration of Nigella sativa oil in the same dose as group IV for 28 days. At the end of experiments, the animals were sacrificed and blood examined for norepinephrine, epinephrine, serotonin, histamine and histaminase enzyme activity. The result of the present study showed that microwaves produced significant reduction of histaminase activity significant increase in histamine, serotonin, norepinephrine and epinephrine, all were highly significantly changed in acute group of irradiation


Sujets)
Animaux de laboratoire , Sérotonine/sang , Catécholamines/sang , Histamine/sang , Agents protecteurs , Plantes médicinales , Diabète expérimental , Rats , Streptozocine , Triglycéride , Glycémie , Cholestérol , Insuline , Animaux de laboratoire
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