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Rev. bras. cir. cardiovasc ; Rev. bras. cir. cardiovasc;34(3): 297-304, Jun. 2019. tab, graf
Article de Anglais | LILACS | ID: biblio-1013476

RÉSUMÉ

Abstract Objectives: To investigate the association between clinical hematologic parameters and saphenous vein graft failure after on-pump coronary artery bypass surgery. Methods: A total of 1950 consecutive patients underwent isolated on-pump coronary artery surgery between November 2010 and February 2013. Of these, 284 patients met our inclusion criteria; their preoperative clinical hematological parameters were retrospectively obtained for this cohort study. And of them, 109 patients underwent conventional coronary angiography after graft failure was revealed by coronary computed tomography angiography. The primary endpoint was to catch at least one saphenous vein graft stenosis or occlusion following the coronary angiogram. We then analyzed risk factors for graft failure. In sequential or T grafts, each segment was analyzed as a separate graft. Results: In logistic regression analysis, older age, platelet distribution width, and diabetes mellitus were identified as independent predictors of saphenous vein graft failure (P<0.). In contrast, preserved ejection fraction value favored graft patency (P<0.001). Conclusion: Increased platelet distribution width is easily measurable and can be used as a simple and valuable marker in the prediction of saphenous vein graft failure.


Sujet(s)
Humains , Mâle , Femelle , Adulte , Adulte d'âge moyen , Sujet âgé , Sujet âgé de 80 ans ou plus , Veine saphène/transplantation , Plaquettes/physiologie , Degré de perméabilité vasculaire/physiologie , Pontage aortocoronarien/effets indésirables , Numération des plaquettes , Valeurs de référence , Veine saphène/physiopathologie , Maladie des artères coronaires/étiologie , Échocardiographie , Modèles logistiques , Pontage aortocoronarien/méthodes , Valeur prédictive des tests , Études rétrospectives , Facteurs de risque , Courbe ROC , Facteurs âges , Coronarographie/méthodes , Échec thérapeutique , Statistique non paramétrique , Tests hématologiques
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