Primary cutaneous amelanotic melanoma and gastrointestinal stromal tumor in synchronous evolution

Abstract: Gastrointestinal stromal tumor is rare digestive tract mesenchymal tumor, most often in the wall of the stomach. It is a benign neoplasm, but it can become malignant if not treated. We report a case of gastrointestinal stromal tumor that was discovered after abdominal ultrasonography during staging of a patient with primary cutaneous amelanotic melanoma. Mutation in the tyrosine kinase receptor could explain the development of two types of tumors in the same patient.

Case report: dermoscopic and histological aspects of skin graft and perigraft hyperpigmentation in acral location

Little is known about the use of dermoscopy in skin grafting. We describe the case of a patient with skin grafting and surrounding pigmentation on acral region. The dermoscopic findings were similar to those of benign acral lesions (lattice-like pattern) and reactive pigmentations (fine striae). Histopathology revealed pigment leakage and increased number of melanocytes. It is believed that this phenomenon occured as the result of an inflammatory stimulus.

Doença de Behçet e tromboembolismo múltiplo / Behçet?s disease and multiple thromboembolism

A doença de Behçet (DB) é uma vasculite sistêmica, recorrente e crônica com manifestações que incluem úlceras orogenitais, uveíte, sinovite, tromboflebite e sintomas envolvendo o sistema nervoso central, trato gastrointestinal e pulmão. Apresenta etiologia desconhecida e diagnóstico baseado em critérios clínicos. A maioria dos casos apresenta manifestações benignas, no entanto, ocasionalmente cursa com trombose de grandes vasos que podem levar ao óbito. Os autores descrevem um caso peculiar, tanto pela dificuldade diagnóstica quanto pela gravidade das manifestações vasculares, e desfecho letal.