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1.
Journal of Korean Neurosurgical Society ; : 148-150, 2010.
Article Dans Anglais | WPRIM | ID: wpr-95220

Résumé

Osteolipoma is an ossified lipoma with distinct components of fat and bone. We present a case of interhemispheric osteolipoma associated with total agenesis of the corpus callosum. A 20-year-old man complained of severe headache, nausea and vomiting. Brain computed tomography showed a low-density mass in an interhemispheric fissure, with high T1 and T2 magnetic resonance signals compatible with fat. The mass measured 4.9 x 2.9 cm in size and showed peripheral calcifications. There was another small piece of same signal mass within the lateral ventricular choroid plexus. The interhemispheric lesion was removed by an interhemispheric approach. Osteolipoma is rare in interhemispheric region, however, it should be a differential diagnosis of lesions with fat intensity mass and calcifications.


Sujets)
Humains , Jeune adulte , Encéphale , Plexus choroïde , Corps calleux , Diagnostic différentiel , Céphalée , Lipome , Spectroscopie par résonance magnétique , Nausée , Vomissement
2.
Journal of Korean Medical Science ; : 83-87, 2001.
Article Dans Anglais | WPRIM | ID: wpr-151873

Résumé

The purpose of this preliminary study is to elucidate that vascular endothelial growth factor (VEGF) influences contrast enhancement of hepatic tumors on computed tomography (CT). Fourteen patients with hepatic tumors (11 hepatocellular carcinomas; 3 metastatic cancers) underwent a dual-phase dynamic helical CT or computed tomographic hepatic arteriography. The attenuation of each mass was determined as hyperattenuation, isoattenuation or hypoattenuation with respect to the adjacent nontumorous parenchyma. Gun-needle biopsy was done for each tumor, and paraffin sections were immunostained with anti- VEGF antibody by the avidin-biotin-peroxidase complex method. The pathologic grade was made by intensity (1 +, 2+, 3+) and area (+/-, 1 +, 2+). The tumor ranged 2.0-14.0 cm in size (mean, 5.8 cm). In arterial phase, the intensity was not correlated with the degree of enhancement (p=0.086). However, the correlation between the attenuation value of hepatic arterial phase and the area of positive tumor cells was statistically significant (p=0.002). VEGF may be the factor that enhances the hepatic mass with water-soluble iodinated contrast agent in CT.


Sujets)
Adulte , Sujet âgé , Femelle , Humains , Mâle , Perméabilité capillaire , Facteurs de croissance endothéliale/physiologie , Facteurs de croissance endothéliale/analyse , Tumeurs du foie/imagerie diagnostique , Tumeurs du foie/vascularisation , Lymphokines/physiologie , Lymphokines/analyse , Adulte d'âge moyen , Études prospectives , Amélioration d'image radiographique , Tomodensitométrie
3.
Journal of the Korean Cancer Association ; : 1087-1093, 1999.
Article Dans Coréen | WPRIM | ID: wpr-185444

Résumé

PURPOSE: Angiogenesis plays an important role in the growth, progression and metastasis of solid tumors. Vascular endothelial growth factor (VEGF) was thought to be one such angiogenic factor and was also thought to be a selective mitogen for endothelial cells. The purpose of this retrospective study was to evaluate for prognostic significance of VEGF in stomach cancer. MATERIALS AND METHODS: The sections of formalin-fixed, paraffin embedded from 55 stomach cancer were stained immunohistochemically for VEGF. The rate of VEGF expression and correlation between expression of VEGF and other prognostic factor of stomach cancer were studied. RESULTS: There were 20 cases (36.4%) of VEGF-positive and 35 cases (63.6%) of VEGF- negative. There were no significant difference between VEGF expression and the histologic type, differentiation, depth of invasion of histologic stage, lymph node involvement. The frequency of hepatic recurrence was higher in patients with VEGF-positive tumor than that af patient with negative tumor (p=0.007). The prognosis of the patients with VEGF positive tumor was worse than that of patients with VEGF negative tumor (p=0.0214). CONCLUSION: There was a closely significant between positive expression of VEGF and a high incidence of hepatic metastasis, low survival rate. The expression of VEGF could be considered to be one of useful prognostic factor in human gastric carcinoma


Sujets)
Humains , Agents angiogéniques , Cellules endothéliales , Incidence , Noeuds lymphatiques , Métastase tumorale , Paraffine , Pronostic , Récidive , Études rétrospectives , Tumeurs de l'estomac , Estomac , Taux de survie , Facteur de croissance endothéliale vasculaire de type A
4.
Journal of the Korean Cancer Association ; : 1168-1178, 1999.
Article Dans Coréen | WPRIM | ID: wpr-174961

Résumé

PURPOSE: This study was aimed to determine the role of the VEGF and MVD expression in infiltrating ductal carcinoma of breast and to observe the correlation between the expression of these VEGF/MVD, and other prognostic factors. MATERIALS AND METHODS: Immunohistochemical staining of VEGF and MVD with monoclonal antibody in pathologic specimens of 35 patients of infiltrating ductal carcinoma of breast was carried out. Reiationship between the expression of the VEGF/MVD and prognostic factors were assessed. RESULTS: The VEGF/MVD expression was closely related to tumor size, lymph node metastasis, and clinical stage, but not related to histologic grade, nuclear grade, estrogen receptor, and progestrone receptor. And the VEGF expression was closely related to MVD. CONCLUSION: The VEGF expression and microvessel density in infiltrating ductal carcinoma of breast may play an important prognostic factors, closely related to the tumor size, lymph node metastasis, and stage.


Sujets)
Humains , Tumeurs du sein , Région mammaire , Carcinome canalaire , Oestrogènes , Noeuds lymphatiques , Microvaisseaux , Métastase tumorale , Facteur de croissance endothéliale vasculaire de type A
5.
Journal of the Korean Ophthalmological Society ; : 491-498, 1993.
Article Dans Coréen | WPRIM | ID: wpr-34774

Résumé

Acute and long-term effects of the noncontact transscleral diode laser cyclophotocoagulation were studied in 6 pigmented rabbits used laser power level was 0.15J, 0.25J, 0.5J and 0.75J. Each eyeballs was enuleated 1.7 and 21 days after cyclophotocoagulation for histopathologic examination. The findings with diode laser were coagulation necrosis of pigmented epitihelium, nonpigmented epitihelium and stroma, congestion of vessel, pigment dispersion and detachment of pigment epithelium. Twenty one days after laser treatment, the light microscopic examination revealed atrophy of nonpigmented epithelium and pigmented epithelium, fibrosls, pigment laden macrophages. These changes were obvious in rabbits treated with a power more than 0.5J. It is suggested that noncontact trasnscleral cyclophotocoagulation with diode laser is useful in lowering intraocular pressure.


Sujets)
Lapins , Atrophie , Épithélium , Oestrogènes conjugués (USP) , Pression intraoculaire , Lasers à semiconducteur , Macrophages , Nécrose
6.
Journal of the Korean Cancer Association ; : 664-672, 1993.
Article Dans Coréen | WPRIM | ID: wpr-41115

Résumé

No abstract available.


Sujets)
Humains , Traitement médicamenteux , Tumeurs du poumon , Poumon
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